| 正加速度对大鼠血浆和丘脑内皮素含量的影响 |
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| 引用本文： | 俞启福,杨晔,赵云涛,李庆棣,郝唯蔚,李鸣皋,秦素清,韩玉玲.正加速度对大鼠血浆和丘脑内皮素含量的影响[J].南京军医学院学报,1994(3). |
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| 作者姓名： | 俞启福 杨晔 赵云涛 李庆棣 郝唯蔚 李鸣皋 秦素清 韩玉玲 |
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| 作者单位： | 海军总医院空潜科 北京100037 |
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| 摘 要： | 为了观察不同正加速度(+Gz)负荷(即头脚向惯性力与重力相比的倍数)对血浆及丘脑内皮素(ET)含量的影响,我们对36只Wistar大鼠分别进行了+6Gz和+10Gz的急性暴露实验,并以+1Gz暴露为对照.结果发现,+6Gz和+10Gz暴露后,血浆ET含量明显增加(P<0.05或0.01),丘脑的ET含量明显下降(P
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| 关 键 词： | 正加速度 内皮素类 丘脑 |
Effect of Positive Accelerration Stress on Contents of Plasma and Thalamus Endothelin in Rats |
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| Yu Qifu,Yang Ye,Zhao Yuntao,Li Qingdi,Hao Weiwei,Li Minggao,Qin Suqing,Han Yuling.Effect of Positive Accelerration Stress on Contents of Plasma and Thalamus Endothelin in Rats[J].Journal of Nanjing Military Medical College,1994(3). |
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| Authors: | Yu Qifu Yang Ye Zhao Yuntao Li Qingdi Hao Weiwei Li Minggao Qin Suqing Han Yuling |
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| Institution: | Yu Qifu,Yang Ye,Zhao Yuntao,Li Qingdi,Hao Weiwei,Li Minggao,Qin Suqing,Han Yuling Department of Aviation and Diving Medicine,Naval General Hospital,Beijing 100037 |
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| Abstract: | In order to observe the effect of the positive acceleration stress on the con-tents of both plasma and thalamus endothelin (ET),the acute exposure of+6Gz and +10Gz was carried out in 36 Wistar rats,and the exposure of + IGz used as control group. The re-sults showed that the plasma ET content after exposure with +6Gz and +10Gz was signifi-cantly increased(P<0. 05 or 0. 01),the thalamus ET content was significantly decreased (P <0. 01 or 0. 001). The plasma ET and thalamus ET have different physiological functions. The increase of plasma ET content may cause strong contraction of coronary arteries and pe-ripheral blood vessels,reduction of the blood backflow amount and weakening of the pumping action of the heart. The decrease of the thalamus ET content may cause reduction of intracel-lular ionized calcium and lowering of the excitement of the central nervous system. |
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| Keywords: | positive acceleration stress endothelins thalamus |
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