Allergic airway disease caused by methyl tetrahydrophthalic anhydride in epoxy resin |
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| Authors: | J Nielsen H Welinder S Skerfving |
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| Institution: | Department of Occupational and Environmental Medicine, University Hospital, Lund, Sweden. |
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| Abstract: | Work-associated rhinitis and asthma occurred in a subject exposed to methyl tetrahydrophthalic anhydride (MTHPA) used as a curing agent in an epoxy resin system. He displayed bronchial hyperreactivity in provocation with methacholine, as well as skin prick test positivity and specific immunoglobulin E (IgE) serum antibodies, against a conjugate of MTHPA and human serum albumin. Thus, it seems likely that the disease was caused by an IgE-mediated allergy. |
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