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| 乌司他丁在重度烧伤中应用进展 | |
| 引用本文： | 生孟军,王雅冰,张歆媛. 乌司他丁在重度烧伤中应用进展[J]. 中国烧伤创疡杂志, 2011, 23(6): 475-477 |
| 作者姓名： | 生孟军 王雅冰 张歆媛 |
| 作者单位： | 1. 中国石油天然气集团公司中心医院烧伤科,河北廊坊,065000 2. 河北医科大学, 河北石家庄,050017 3. 天津医科大学,天津,300070 |
| 摘 要： | 严重烧(创)伤后,常常伴有某些细胞因子表达异常,并直接影响到疾病的发展和预后,寻找改善上述病理变化的治疗药物和方法成了烧伤医学重点研究的课题之一.目前多数学者认为,乌司他丁(UTI)在改善危重疾病的细胞因子异常变化方面具有一定作用.为了进一步探讨UTI在烧伤、创伤中的治疗作用,作者复习了近年来有关乌司他丁的药理作用、临床应用效果及作用机制等文献,旨在为烧伤和创伤基础研究与临床应用提供参考依据. |
| 关 键 词： | 烧伤 乌司他丁 理化性质 药理作用 临床应用 |
Application Progress of UTI in the Treatment of Major Burns |
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| SHENG Meng-jun , WANG Ya-bing , ZHANG Xin-yuan. Application Progress of UTI in the Treatment of Major Burns[J]. The Chinese Journal of Burns Wounds & Surface Ulcers, 2011, 23(6): 475-477 | |
| Authors: | SHENG Meng-jun WANG Ya-bing ZHANG Xin-yuan |
| Affiliation: | SHENG Meng-jun, WANG Ya-bing, ZHANG Xin-yuan(Burn Department of Central Hospital of China National Petroleum Cooperation, Langfang, Hebei Province 065000, China ; Hebei Medical University, Shijiazhuang 050017, China; Tianjin Medical University, Tianjin 300070, China ) |
| Abstract: | Abnormal cytokines expression usually occurs ‘after major burns, and directly ＇affects disease progress and prognosis. It has been an importaat research subject to find an approach or drug to improve above pathological changes. Many researchers believe, at present, that UTI acts on improving the abnormal cytokines changes of critical illness. To further explore the role of UTI in the treatment of burn and trauma, we reviewed all the recent papers about pharmacological actions, clinical efficacy and mechanism of UTI to provide a reference for basic research and clinical application of burn and trauma. |
| Keywords: | Burn UTI Physieochemical property Pharmacological actions Clinical application |
| 本文献已被 维普 万方数据 等数据库收录！ | |