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Modification of Biological Activity of Lipopolysaccharide in the Complex with Chitosan
Authors:I. M. Ermak  V. N. Davydova  V. I. Gorbach  E. L. Berdyshev  T. A. Kuznetsova  I. A. Ivanushko  A. K. Gazha  T. P. Smolina  T. S. Zaporozhets  T. F. Soloveva
Affiliation:Pacific Ocean Institute of Bioorganic Chemistry, Far-Eastern Division of the Russian Academy of Sciences, Vladivostok. iren@piboc.dvo.ru
Abstract:In the complex with chitosan, lipopolysaccharide partially lost its ability to induce lymphokines tumor necrosis factor and interleukin-8, but retained immunostimulating properties and increased phagocytic function of macrophages by improving digestion of bacteria.
Keywords:lipopolysaccharide  lipopolysaccharide-chitosan complex  lymphokines  immunity
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