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Lethal Factor and Anti-Protective Antigen IgG Levels Associated with Inhalation Anthrax,Minnesota, USA
Authors:Mark D. Sprenkle  Jayne Griffith  William Marinelli  Anne E. Boyer  Conrad P. Quinn  Nicki T. Pesik  Alex Hoffmaster  Joseph Keenan  Billie A. Juni  David D. Blaney
Affiliation:Hennepin County Medical Center, Minneapolis, Minnesota, USA (M.D. Sprenkle, W. Marinelli); ;Minnesota Department of Health, St. Paul, Minnesota, USA (J. Griffith, B.A. Juni); ;Centers for Disease Control and Prevention, Atlanta, Georgia, USA (A.E. Boyer, C.P. Quinn, N.T. Pesik, A. Hoffmaster, D.D. Blaney); ;University of Minnesota, Minneapolis (J. Keenan)
Abstract:Bacillus anthracis was identified in a 61-year-old man hospitalized in Minnesota, USA. Cooperation between the hospital and the state health agency enhanced prompt identification of the pathogen. Treatment comprising antimicrobial drugs, anthrax immune globulin, and pleural drainage led to full recovery; however, the role of passive immunization in anthrax treatment requires further evaluation.
Keywords:Inhalation anthrax   anthrax   anthrax immune globulin   critical care   anti-protective antigen   anti-PA   lethal factor   Minnesota   USA   Bacillus anthracis   zoonoses
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