Manipulation for degenerative lumbar spondylolisthesis: A systematic review of randomized controlled trialsOA |
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作者姓名: | Zhiwei Liu Xiaokuan Qin Kai Sun He Yin Xin Chen Bowen Yang Xu Wang Xu Wei Liguo Zhu |
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作者单位: | 1. School of Postgraduate, Beijing University of Chinese Medicine;2. Department of Spine, Wangjing Hospital, China Academy of Chinese Medical Sciences;3. Department of Academic Development, Wangjing Hospital, China Academy of Chinese Medical Sciences |
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摘 要: | Objective: To assess the effectiveness and safety of manipulation intervention for degenerative lumbar spondylolisthesis(DLS).Methods: This is a systematic review and meta-analysis. A full-scale retrieval method was performed until February 1, 2021, including nine databases. The homogeneity of different studies was summarized using the Review Manager. The quality of studies was determined with the Cochrane risk-of-bias tool.The evidence quality was graded with the Grading of Recommendations, Ass...
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收稿时间: | 22 December 2021 |
Manipulation for degenerative lumbar spondylolisthesis: A systematic review of randomized controlled trials |
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Institution: | 1. School of Postgraduate, Beijing University of Chinese Medicine, Beijing, 100029, China;2. Department of Spine, Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, 100102, China;3. Department of Academic Development, Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, 100102, China |
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Abstract: | ObjectiveTo assess the effectiveness and safety of manipulation intervention for degenerative lumbar spondylolisthesis (DLS).MethodsThis is a systematic review and meta-analysis. A full-scale retrieval method was performed until February 1, 2021, including nine databases. The homogeneity of different studies was summarized using the Review Manager. The quality of studies was determined with the Cochrane risk-of-bias tool. The evidence quality was graded with the Grading of Recommendations, Assessment, Development, and Evaluations approach.ResultsA total of 6 studies involving 524 participants were included. The review demonstrated that manipulation has statistically significant improvements for treating DLS according to Japanese Orthopedic Association scores (mean difference, 3.76; 95% confidence interval, 2.63 to 4.90; P < .001) and visual analog scale scores (mean difference, ?1.50; 95% confidence interval, ?1.66 to ?1.33; P < .001) compared to the control group. One study reported that the difference in the Oswestry Disability Index between the traction group and the combination of manipulation and traction group was statistically significant (P < .05), while another reported that manipulation treatment can significantly improve the lumbar spine rotation angle on X-ray images compared with the baseline data (P < .05). Moreover, the manipulation group (experimental group) had fewer adverse events than the lumbar traction group (control group).ConclusionManipulation intervention is more effective and safer for DLS. Nevertheless, large-scale randomized controlled trials are required to confirm the current conclusions. |
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Keywords: | Manipulation Degenerative lumbar spondylolisthesis Meta-analysis Japanese orthopedic association Oswestry disability index Visual analog scale Randomized controlled trial |
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