| 急性脑梗死患者血糖、肌酐、尿素氮及血清ET-1水平的研究 |
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| 引用本文： | 段新旺,黄亮,李辉华.急性脑梗死患者血糖、肌酐、尿素氮及血清ET-1水平的研究[J].中华急诊医学杂志,2011,20(10). |
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| 作者姓名： | 段新旺 黄亮 李辉华 |
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| 作者单位： | 1. 南昌大学第一附属医院急诊科, 南昌,330006
2. 南昌大学第一附属医院神经内科, 南昌,330006 |
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| 摘 要： | 目的 探讨急性脑梗死患者血糖、肌酐、尿素氮及血清内皮素( endothelin-1,ET-1)水平的变化及其神经功能缺损程度与ET-1水平的关系.方法 用125I放射免疫法分析50例发病在24h内的急性脑梗死患者与对照组50例同期非神经系统疾病患者血清ET-1水平的变化,并比较其血糖、肌酐及尿素氮水平.结果 急性脑梗死组血糖、肌酐及尿素氮水平差异无统计学意义(P＞0.05),但血清ET-1水平显著性高于对照组(P＜0.01),且急性脑梗死血清ET-1水平的变化与其神经功能缺损程度显著性相关,不同组间均P值＜0.01.结论 血清ET-1水平可作为急性脑梗死发生预测及预后评估的指标之一.
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| 关 键 词： | 急性脑梗死 ET-1 神经功能缺损 血糖 肌酐 尿素氮 |
Study on glucose, creatinine, urea nitrogen and serum ET-1 of patients with acute cerebral infarction |
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| DUAN Xin-wang,HUANG Lian,LI Hui-hua.Study on glucose, creatinine, urea nitrogen and serum ET-1 of patients with acute cerebral infarction[J].Chinese Journal of Emergency Medicine,2011,20(10). |
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| Authors: | DUAN Xin-wang HUANG Lian LI Hui-hua |
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| Abstract: | Objective To study glucose,creatinine,urea nitrogen and serum ET-1 of patients with acute cerebral infarction,and to explore the relationship between neurologic impairment and ET-1 levels.Methods The glucose,creatinine,urea nitrogen and serum ET-1 were retrospectively analyzed in 50 patients with acute cerebral infarction ( ＜ 24 h) and 50 patients with non-neurological diseases.ET-1 determined by 125I radioimmunoassay.Results There were no significant differences in glucose,creatinine and urea nitrogen of acute cerebral infarction ( P ＞ 0.05 ) ; Compared to the control groups,ET-1 levels was significantly higher ( P ＜ 0.01 ),and levels of serum ET-1 in acute cerebral infarction were significantly correlated with their neurological deficits ( P ＜ 0.01 ).Conclusions Levels of serum ET-1 can severd as diagnostic and prognostic indicator of acute cerebral infarction. |
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| Keywords: | Acute cerebral infarction ET-1 Neurologic impairment Glucose Creatinine Urea nitrogen |
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