Postmortem angiographic and pathologic-anatomic findings in coronary heart disease: A comparative study using planimetry |
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Authors: | J Staiger MD C P Adler H Dieckmann J Barmeyer |
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Institution: | (1) Zentrum Innere Medizin and Pathologisches Institut (Ludwig Aschoff Haus), University of Freiburg, Hugstetter Str. 55, D-7800 Freiburg, FRG |
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Abstract: | Comparisons of the results of angiographic and pathologic-anatomic estimations of the degree of coronary artery stenosis are
rare and the findings contradictory. In the present study, postmortem examinations were carried out on 26 hearts with coronary
artery disease. Quantitative planimetric measurements of 203 coronary artery cross-sections were performed and compared with
the results of postmortem coronary angiograms. Using a score rating scale, a highly significant difference (P<0.001) between the angiographic and morphologic findings was detected, with the degree of stenosis underestimated angiographically
in 96 of the 203 sections (47%), overestimated in 18 (9%), and correctly estimated in 89 (44%). The tendency to underestimation
was equal in all of the coronary arteries (left anterior descending, circumflex, and right coronary arteries); there were
no statistically significant differences (P<0.20,P<0.30,P<0.10). The frequency of angiographic underestimation of the degree of morphologic stenosis—especially in critical stenoses
of more than 60%—has important implications in the assessment of whether coronary artery surgery is warranted.
Dedicated to Prof. Dr. Walter Sandritter on the occasion of his 60th birthday |
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Keywords: | Coronary angiography Coronary arteries stenosis |
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