| 兔鼻窦炎模型骨质重塑的CT观察 |
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| 引用本文： | 张晶,周兵,刘中林,李书玲,范尔钟,崔顺九.兔鼻窦炎模型骨质重塑的CT观察[J].中国耳鼻咽喉头颈外科,2009(4):202-205. |
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| 作者姓名： | 张晶 周兵 刘中林 李书玲 范尔钟 崔顺九 |
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| 作者单位： | 首都医科大学附属北京同仁医院;首都医科大学附属北京同仁医院耳鼻咽喉头颈外科;耳鼻咽喉头颈科学教育部重点实验室（首都医科大学）;首都医科大学附属北京同仁医院放射科;北京市耳鼻咽喉科研究所; |
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| 摘 要： | 目的观察不同造模时间兔鼻窦炎模型鼻寞骨质重塑的CT表现及时间相关趋势。方法采用窦口阻塞加细菌接种方法建立兔鼻窦炎模型，按造模时间不同分为2、4、6、8、12周组，每组8只。分别进行鼻窦CT扫描。主要观察指标包括骨质破坏和骨质增生：次要指标包括软组织变化等共6项。结果早期模型主要表现为骨质破坏，6周及以后的模型除骨质破坏，还出现骨质增生。其中，2周和4周组均有6只动物出现骨质破坏；后3组出现骨质破坏和骨质增生动物的数量分别是7、7、6只和3、5、7只。其余指标无明显差异。结论免鼻窦炎模型鼻窦骨质重塑特征在CT主要表现为骨质破坏和骨质增生；早期以骨质破坏为主，6周及以后表现为骨质破坏和骨质增生共存，且随时间延长，骨质增生更为明显。
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| 关 键 词： | 鼻窦炎 模型 动物 骨重建 体层摄影术 X线计算机 |
An observation of the bone remodeling in rabbits sinusitis model with CT scan |
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| Institution: | ZHANG Jing, ZHOU Bing, LIU Zhonglin, LI Shuling, FAN Erzhong, CUI Shunjiu(1 2006 Post-Graduate Student, 2 Department of Otolaryngology Head and Neck Surgery, Key Laboratory of Otolaryngology Head and Neck Surgery (Capital Medical University) , Ministery of Education, 3 Department of Radiology, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, China; 4 Beijing Institute of Otolaryngology, Beijing, 100005, China) |
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| Abstract: | OBJECTIVE To evaluate the bone remodeling in rabbits sinusitis model by CT scan and observing the CT manifestations and time sequence related tendency.METHODS Forty white rabbits(New Zealand) were divided into 5 groups and each group had 8 rabbits.After the sinusitis models were made by incomplete ostia-obstructed and inoculated staphylococcus,we choose one group to be detected by CT scan separately at each time point(2,4,6,8 and 12 weeks after operation).The items we are going to evaluate conclude bone des... |
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| Keywords: | Sinusitis Models Animal Bone Remodeling Tomography X-Ray Computed |
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