| 人参茎叶二醇组和三醇组皂甙对血压等作用影响 |
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| 引用本文： | 杨世杰,周鸣,谢湘林,曹延年,王丹.人参茎叶二醇组和三醇组皂甙对血压等作用影响[J].吉林大学学报(医学版),1991(1). |
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| 作者姓名： | 杨世杰 周鸣 谢湘林 曹延年 王丹 |
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| 作者单位： | 白求恩医科大学基础医学院药理教研室
(杨世杰，周鸣，谢湘林，曹延年)，白求恩医科大学基础医学院数理教研室(王丹) |
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| 摘 要： | 本实验观察了人参茎叶二醇组和三醇组皂甙静脉注射后对血压等作用。二醇组皂甙(30mg/kg)可引起血压明显下降,其降压作用可被阿托品对抗、三醇组皂甙(70mg/kg)可引起血压升高其升压作用不被妥拉苏林和心得安所对抗。二种皂甙对去甲肾上腺素引起的升压作用无影响。二种皂甙在引起血压变化时并未引起心率和呼吸的明显改变。
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| 关 键 词： | 血压 药物作用 人参茎叶二醇组皂甙(PDS) 人参茎叶三醇组皂甙(PTS) |
EFFECT OF PDS AND PTS ON BLOOD PRESSURE, HEART RATE AND RESPIRATION IN ANAESTHETIZED RATS |
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| Yang Shijie,Zhou Ming,Xie Xiang lin,Cao Yannian.EFFECT OF PDS AND PTS ON BLOOD PRESSURE, HEART RATE AND RESPIRATION IN ANAESTHETIZED RATS[J].Journal of Jilin University: Med Ed,1991(1). |
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| Authors: | Yang Shijie Zhou Ming Xie Xiang lin Cao Yannian |
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| Institution: | Department of Pharmacology |
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| Abstract: | The effect of PDS and PTS given intravenously on the blood pressure in aenesthetized rats was studied. PDS(30mg/kg)produced a significant hypotensive effect which could be antagonized by atropine, while PTS (70mg/kg) produced a hypertensive effect which could not be antagonized by tolazoline and propranolol. When PDS and PTS affected the blood pressure, they had no effect on the heart rate and respiration, and also did not affect the hypertensive action of norepinephrine. |
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| Keywords: | Blood pressure PDS(Panaxadiol saponin) PTS (Panaxatriol saponin) NE (Norepinephrine) |
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