| PRELIMINARY COMPARISON OF SENSITIVITY TOWARD PARVO VIRUS H-1 OF HUMAN HEP ATOM A CELLS AND PARAHEPATOMA TISSUE |
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| 作者姓名： | 林万敏 崔衍贞 俞伯根 罗祖玉 林芷英 |
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| 作者单位： | Department of Physiology and Biophysics，Fudan University，Department of Physiology and Biophysics，Fudan University，Department of Physiology and Biophysics，Fudan University，Department of Physiology and Biophysics，Fudan University，Institute of Liver Cancer，Zhong Shan Hospital，Shanghai Medical University |
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| 摘 要： | Preliminary observations on the result of infection by parvovirus of primary cultured cells of human hepatoma and parahepatoma tissue were reported. Human hepatoma and parahepatoma tissue were obtained by the culture method of tissue fragment plating. It was observed that their respective sensitivity to parvovirus H-1 was different. H-1 had inhibitory effect on epithelial cells of hepatoma tissue but without any significant effect on fibroblasts simultaneously, H-l had no effect on epithelial cells and fibroblasts of parahepatoma tissue. Further investigation of the relationship between parvovirus and hepatoma would be helpful not only in elucidating the mechanism of carcinogenesis and its suppression but also in the search of new approach for the treatment of hepatoma.
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