男性乳腺增生症患者血浆性激素水平测定

为研究性激素与男性乳腺增生症的关系，用RIA法测定了男性乳腺增生症患者的血浆性激素水平。78例男性乳腺增生症患者为研究组（按年龄又分为青年组≤30岁，中年组30～60岁，老年组≥60岁），24例健康男性为对照组。结果表明男性乳腺增生症患者的E2和E2/T与健康者相比明显增高（P<0.05，<0.01）；研究组中老年组有T降低者的例数与青年组、中年组相比有明显增高（均为P<0.05）。结果提示男性乳腺增生症与性激素水平紊乱有关，主要是雌激素水平上升，老年男性乳腺增生症还与雄激素降低有密切关系。

Determination of Plasma Sex Hormone Levelsin the Male Patients with Gynecomastia

In order to study the relationship between sex hormone and gynecomastia, the levels of plasma sex hormone in the male patients with gynecomastic were determined by using radioactive immune assay. Seventy-eight gynecomastic patients were regarded as the experimental group which was divided into 3 subgroups: the youth group with the age ≤30 years old, the middle-aged group with the age ranging from 30 to 60 years old and the old-aged group with the age ≥60 years old in the light of age and 24 normal men served as control group. The results showed that the levels of E2 and E2/T in the gynecomastia patients were much higher than in the control group (P<0.05, 0.01)；In the experimental group, the ratio of T reduction in the old-aged group was much higher than in the youth group or the middle-aged group（P<0.05). In conclusion, gynecomastia was related to the dysfunction of the level of sex hormone, to a large extent, with the increasing of estrogen. In addition, senile gynecomasti was closely related with the decreasing of male hormone.