|
|||||
|
|
Synthesis of Some New 2-Substituted 3-[4-(N′-Arylsulphonylbiguanido)phenyl]quinazolin-4-one Hydrochlorides as Potential Anthelminthic Agents |
|
| Authors: | Jagdish S. Shukla Kanchan Agarwal Renu Rastogi |
| Abstract: | The title compounds 3--37 have been synthesised. Their in vivo cestodicidal activities were evaluated against Hymenolepis nana infection in rats. Compound 32 was found to be the most active of the series showing 81.0% clearance of infection at a dose of 250 mg/kg for 3 days. |
| Keywords: | |