丁苯酞联合血栓通治疗急性脑梗死临床研究

目的 探讨丁苯酞联合血栓通治疗急性脑梗死(ACI)的临床疗效.方法 选取医院2019年1月至2020年1月收治的ACI患者200例,按随机数字表法分为对照组和观察组,各100例.两组患者均予基础治疗及血栓通注射液静脉滴注,观察组患者加用丁苯酞氯化钠注射液静脉滴注.两组均连续治疗7 d.结果 观察组总有效率为86.00％...

Clinical Study of Butylphthalide Combined with Xueshuantong in the Treatment of Acute Cerebral Infarction

Objective To investigate the effect of butylphthalide combined with Xueshuantong in the treatment of acute cerebral infarction(ACI).Methods A total of 200 patients with ACI admitted to the hospital from January 2019 to January 2020 were selected and divided into the control group and the observation group according to the random number table method,with 100 cases in each group.The patients in the two groups were treated with basic treatment and Xueshuantong Injection,on this basis,the patients in the observation group were treated with Butylphthalide Sodium Chloride Injection.Both groups were continuously treated for 7 d.Results The total effective rate of the observation group was 86.00%,which was significantly higher than 59.00%of the control group(P<0.05).After treatment,the mean blood flow(Q;)and mean blood flow velocity(V;)of arteria carotis communis in the observation group were significantly higher than those in the control group,while the peripheral resistance(R;)and dynamic resistance(DR)of arteria carotis communis in the observation group were significantly lower than those in the control group(P<0.05).The score of National Institutes of Health Stroke Scale(NIHSS)in the observation group was significantly lower than that in the control group,while the score of Mini-Mental State Examination(MMSE)in the observation group was significantly higher than that in the control group(P<0.05).The incidence of adverse reactions in the observation group was similar to that in the control group(16.00%vs.13.00%,P>0.05).Conclusion Butylphenol combined with Xueshuantong in the treatment of patients with ACI can effectively improve cerebral hemodynamics and cognitive function.