肾康注射液对糖尿病肾病血液流变学的临床观察

目的探讨肾康注射液对糖尿病肾病（DN）患者血液流变学的影响。方法糖尿病肾病68例患者随机分为治疗组（35例）和对照组（33例）。对照组常规降压、降脂、抗凝、降糖治疗。在常规治疗的基础上,治疗组给予肾康注射液60mL＋0.9%氯化钠注射液250mL静脉滴注,1次/d。两组疗程均为2周。比较两组治疗前、后血糖、肾功能、尿微量蛋白尿和血液流变学测定结果。结果两组治疗前后血糖、肾功能、尿微量蛋白尿、全血粘度、血浆黏度、红细胞压积、纤维蛋白原比较及两组间比较差异有统计学意义（P〈0.05,P〈0.01）。结论肾康注射液可改善糖尿病肾病患者高凝、高脂状态,有助于糖尿病肾病的治疗。

Clinical observation on the effect of Shenkang injection on hemorheology of diabetic nephropathy patients

Objective To explore the effect of Shenkang injection（SKI）,a Chinese herbal medicine on hemorheology of diabetic nephropathy（DN） patients.Methods Sixty-eight diabetic nephropathy patients were randomly divided into the treatment group（35 patients） and the control group（33 patients）.33 patients in the control group were treated with conventional blood pressure reduction,blood fat reduction,anticoagulation and blood sugar reduction therapy for aperiod of 14 days.The patients in treatment were also treatment with conventional therapy mentioned above plus Shenkang injection 60m and 0.9% sodium chloride in 250ml for intravenous drip;Once a day for a course of 14 days.Then the results of treament in both gorups were campared.Results The parameters of blood sugar（FPG,2 hPG）,blood creatinine（cr） and blood urea nitrogen（BUN）,urine trace proteinuria（UAER）,whole blood viscosity,plasma viscosity,red blood cell deposited,fibrinogen in of control group.（P0.05 or P0.01）.Conclusion Shenkang injection（SKJ） can improve the hyper coagulability,hyperlipidemia state and it is conducive to treament of diabetic nephrophathy patients.