Candida albicans and Candida dubliniensis respond differently to echinocandin antifungal agents in vitro |
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Authors: | Jacobsen Mette D Whyte Julie A Odds Frank C |
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Affiliation: | Aberdeen Fungal Group, School of Medical Sciences, Institute of Medical Sciences, University of Aberdeen, Aberdeen, UK. |
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Abstract: | Candida dubliniensis isolates tested for susceptibility to anidulafungin, caspofungin, and micafungin commonly showed artifactual regrowth and/or trailing effects with MIC tests done under conditions involving a high initial yeast concentration. The artifacts were less common with Candida albicans and seldom seen for either species under Clinical and Laboratory Standards Institute method M27-A test conditions. |
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