| 慢性乙型肝炎血清HBV DNA水平与血清ALT的关系 |
| |
| 引用本文： | 胡继伟.慢性乙型肝炎血清HBV DNA水平与血清ALT的关系[J].中国实用医药,2007,2(16):25-26. |
| |
| 作者姓名： | 胡继伟 |
| |
| 作者单位： | 450015,河南省郑州市第六人民医院传染科 |
| |
| 摘 要： | 目的探讨慢性乙型肝炎病毒(HBV)复制水平与丙氨酸氨基转移酶(ALT)之间的关系。方法对180例慢性乙型肝炎患者血清HBV DNA含量采用荧光标记(AmpliSensor)定量PCR方法检测,并比较HBV DNA含量与ALT的关系。结果慢性乙型肝炎轻度、中度患者HBV DNA含量(105.58±1.92,106.27±2.05)与慢性乙型肝炎重度患者HBV DNA含量(105.73±1.90)相比较差异无统计学意义(P>0.05),且不同HBV DNA水平患者的ALT差异无统计学意义(P>0.05)。结论随着肝损害程度的加重,慢性乙型肝炎患者血清HBV DNA基因含量未发生显著变化,同时血清HBV DNA含量与ALT水平无明显关系。
|
| 关 键 词： | 慢性乙型肝炎 乙型肝炎病毒核酸 丙氨酸氨基转移酶 定量聚合酶链反应 |
Quantitative detection of serum HBV DNA in patients with chronic hepatitis B and its relationship with Alanine Transaminase |
| |
| HU Ji-wei.Quantitative detection of serum HBV DNA in patients with chronic hepatitis B and its relationship with Alanine Transaminase[J].China Practical Medical,2007,2(16):25-26. |
| |
| Authors: | HU Ji-wei |
| |
| Abstract: | Objective To explore the relationship between the nucleic acid content of hepatitis B virus and ALT with different clinical types of chronic hepatitis B.Methods The contents of HBV DNA were detected by Fluorescence quantitative PCR and ALT was detected by IRMA.Results There were not significant difference between HBV DNA content and different clinical types of chronic hepatitis B(P>0.05).The contents of HBV DNA had no correlation with ALT(P>0.05).Conclusion There is not a significant correlation between liver inflammation stage and serum HBV DNA content in different clinical types of chronic of hepatitis B. |
| |
| Keywords: | Chronic hepatitis B HBV DNA Alanine transaminase Quantitative PCR |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
