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| 高效液相色谱法测定种子三达丸中芍药苷的含量 | |
| 引用本文： | 张国民,杨工昶,齐赤虹,王海迪.高效液相色谱法测定种子三达丸中芍药苷的含量[J].中国中医药信息杂志,2008,15(10):55-56. |
| 作者姓名： | 张国民 杨工昶 齐赤虹 王海迪 |
| 作者单位： | 1. 开封市食品药品检验所,河南开封,475002 2. 河南省医药学校,河南开封,475001 3. 北京美德森医药技术开发有限公司,北京,100101 |
| 摘 要： | 目的建立高效液相色谱法测定种子三达丸中芍药苷含量的方法。方法色谱柱采用Kromasil-C18（5um，4．6mm×250mm）；流动相为甲醇-水（30：70）；检测波长为230nm；流速为1．0mL／min。结果芍药苷在0．11～2．14ug范围内呈良好的线性关系（r=0．9999，n=5），平均回收率为98．2％（RSD=1．72％，n=6）。结论本方法简便、可靠、准确，可用于该制剂的质量控制。 |
| 关 键 词： | 种子三达丸 芍药苷 高效液相色谱法 含量测定 |
Determination of Peoniflorin in Zhongzi Sanda Pill by HPLC |
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| ZHANG Guo-min,YANG Gong-chang,QI Chi-hong,et al.Determination of Peoniflorin in Zhongzi Sanda Pill by HPLC[J].Chinese Journal of Information on Traditional Chinese Medicine,2008,15(10):55-56. | |
| Authors: | ZHANG Guo-min YANG Gong-chang QI Chi-hong |
| Institution: | ZHANG Guo-min1,YANG Gong-chang2,QI Chi-hong2,et al(1.Kaifeng Institute for Drug Control,Kaifeng 475002,China,2.Henan Medical , Pharmaceutical School,Kaifeng 475001,China) |
| Abstract: | Objective To establish a HPLC method for determination of Peoniflorin in Zhongzi Sanda Pill. Method Kromasil-C18 column （5 um, 4.6 mm× 250 mm） was used. Mobile phase was methanol-water （30 ： 70）. The detective wavelength was at 230 nm. The flow rate was 1.0 mL/min. Results There was a good linear relationship between the injection amount 0.11×2.14ug and a good peak form for Peoniflorin in Zhongzi Sanda Pill The average recovery rate was 98.2% （RSD= 1.72%, n =6）. Conclusion This method is convenient, effective and accurate for the quality control of Peoniflorin in Zhongzi Sanda Pill. |
| Keywords: | Zhongzi Sanda Pill Peoniflorin HPLC content determination |
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