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红花注射液对慢性肾疾病血清纤维化指标表达的临床观察
引用本文:朱晋龙,王素芹,严晓枫.红花注射液对慢性肾疾病血清纤维化指标表达的临床观察[J].河南中医,2011,31(12):1390-1392.
作者姓名:朱晋龙  王素芹  严晓枫
作者单位:淮安市中医院,江苏淮安,223001
摘    要:目的:研究红花注射液对慢性肾脏病患者肾功能、肾纤维化的作用。方法:60例患者随机分为治疗组40例和对照组20例,对照组予以一般治疗和对症治疗,治疗组在对照组治疗的基础上予红花注射液20 mL静滴,日1次,2周为1疗程,1-3疗程后观察红花注射液对慢性肾脏病患者肾功能指标即血清肌酐(Scr)、尿素氮(BUN)、内生肌酐清除率(Ccr)和纤维化指标即血清层粘连蛋白(LN)、Ⅲ型前胶原(PC-Ⅲ)、Ⅳ型胶原(CⅣ)、透明质酸(HA)的影响。结果:与对照组患者比较,治疗组能明显降低慢性肾脏病患者的Scr、BUN、LN、PC-Ⅲ、CⅣ、HA水平。两者比较有统计学意义(P〈0.05)。结论:红花注射液能改善肾纤维化,延缓慢性肾脏病的进程。

关 键 词:红花注射液  慢性肾疾病  肾功能  肾纤维化  Scr  BUN  LN  PC-Ⅲ  CⅣ  HA

Clinical Observation on Effect of Honghua Injection on Expression of Serum Fibrosis Markers in Chronic Kidney Disease
Zhu Jinlong,Wang Suqin,Yan Xiaofeng.Clinical Observation on Effect of Honghua Injection on Expression of Serum Fibrosis Markers in Chronic Kidney Disease[J].Henan Traditional Chinese Medicine,2011,31(12):1390-1392.
Authors:Zhu Jinlong  Wang Suqin  Yan Xiaofeng
Institution:Zhu Jinlong,Wang Suqin,Yan Xiaofeng(Huai'an TCM Hospital,Huai'an,Jiangsu,223001)
Abstract:Objective: To study the effect of Honghua Injection on renal function and renal fibrosis of patients with chronic kidney disease.Methods: 60 patients were randomly divided into treatment group(40 cases)and a control group(20 cases).The control group received general treatment and symptomatic treatment,while the treatment group were given 20ml intravenous injection of safflower injection,once a day and 2 weeks of treatment.After 1-3 courses of treatment observed the effects of Honghua Injection on the renal ...
Keywords:Honghua Injection  chronic kidney disease  renal function  renal fibrosis  Scr  BUN  LN  PC-Ⅲ  C Ⅳ  HA
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