| 舒胃汤对功能性消化不良大鼠血清干细胞因子、一氧化氮的影响 |
| |
| 引用本文： | 郭璇,弭艳红,王小娟,谭华梁,郭建生,徐寅,张鑫,饶文娟,李永静,郭蕾蕾.舒胃汤对功能性消化不良大鼠血清干细胞因子、一氧化氮的影响[J].湖南中医药大学学报,2011,31(9). |
| |
| 作者姓名： | 郭璇 弭艳红 王小娟 谭华梁 郭建生 徐寅 张鑫 饶文娟 李永静 郭蕾蕾 |
| |
| 作者单位： | 1. 湖南中医药大学,湖南长沙,410208
2. 湖南中医药大学第一附属医院,湖南长沙,410007 |
| |
| 基金项目： | 湖南省卫生厅中医药专项基金(2008025); 长沙市科技局项目(K1001061-31) |
| |
| 摘 要： | 目的观察舒胃汤对功能性消化不良(FD)大鼠血清干细胞因子(SCF)、一氧化氮(NO)的影响,探讨舒胃汤治疗FD的作用机制。方法将60只SD大鼠随机分为空白组、模型组、木香顺气丸组、莫沙必利组、舒胃汤低剂量组、舒胃汤高剂量组共6组,每组10只。除空白组外其余5组通过夹尾刺激方法制造功能性消化不良模型。模型组和空白组不给予药物处理,其余各组大鼠分别给予相应药物灌胃治疗14 d。采用ELASA法检测大鼠血清SCF、硝酸还原酶法检测大鼠血清NO含量变化。结果与空白组比较,模型组大鼠血清NO升高,SCF降低(均为P<0.05),差异有统计学意义;舒胃汤治疗后血清SCF升高(P<0.05),NO降低差异有统计学意义(P<0.05)。结论舒胃汤能够调节功能性消化不良大鼠血浆NO、SCF水平的变化,恢复胃肠道运动功能,从而起到对功能性消化不良的治疗作用。
|
| 关 键 词： | 功能性消化不良 胃肠运动 舒胃汤 干细胞因子 一氧化氮 大鼠 柴胡 枳实 |
Effects of Shuwei decoction on serum stem cell factors and nitric oxiode in functional indigestive rats |
| |
| GUO Xuan,MI Yan-hong,WANG Xiao-juan,TAN Hua-liang,GUO Jan-sheng,XU Yin,ZHANG Xin,RAO Wen-juan,LI Yong-jing,GUO Lei-lei.Effects of Shuwei decoction on serum stem cell factors and nitric oxiode in functional indigestive rats[J].Journal of Traditional Chinese Medicine University of Hunan,2011,31(9). |
| |
| Authors: | GUO Xuan MI Yan-hong WANG Xiao-juan TAN Hua-liang GUO Jan-sheng XU Yin ZHANG Xin RAO Wen-juan LI Yong-jing GUO Lei-lei |
| |
| Institution: | GUO Xuan,MI Yan-hong,WANG Xiao-juan,TAN Hua-liang,GUO Jan-sheng,XU Yin,ZHANG Xin,RAO Wen-juan,LI Yong-jing,GUO Lei-lei(1.TCM University of Hunan,Changsha,Hunan 410007,China,2.First Affiliated Hospital,TCM University of Hunan,Hunan 410007) |
| |
| Abstract: | Objective To observe the influences of Shuwei decoction on the content of serum nitric oxiode(NO) and stem cell factors(SCF) in functional dyspepsia(FD) rats and study the acting mechanism of the decoction on FD.Methods Sixty rats were randomly divided into control group,model group,Muxiang Shunqi pills group,Mosapride group,Shuwei decoction high dose group and Shuwei decoction low dose group,10 rats in each group.All the rats except for in control group were induced the FD models by clasping their tails.Ex... |
| |
| Keywords: | functional dyspepsia gastrointestinal motility Shuwei decoction stem cell factors(SCF) nitric oxiode(NO) rats Bupleuri Radix Aurantii Fructus Immaturus |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
