高脂血症与男性勃起功能障碍

勃起功能障碍(ED)是男性,尤其是老年男性的常见病。高脂血症是引起男性ED的重要危险因子之一,流行病学研究发现高密度脂蛋白(HDL)水平的下降和总胆固醇/高密度脂蛋白比值(TC/HDL)的上升与ED有明显相关性。目前研究显示高脂血症引起的动脉狭窄和闭塞可能只是高脂血症引起ED的晚期机制。高脂血症早期即可影响阴茎的内皮细胞、平滑肌细胞及支配阴茎勃起的外周神经而使阴茎勃起功能受损。对高脂血症所致ED的治疗除针对高脂血症的饮食治疗和药物治疗外,针对ED的中药治疗和基因治疗有望成为治疗高脂血症所致ED的重要方法。

Hyperlipidemia and Erectile Dysfunction

Hyperlipidemia is one of the risk factors leading to erectile dysfunction(ED),a common disorder in men,especially in old men.Epidemiological studies have found that the decrease in high density lipoprotein(HDL) and elevation of total cholesterol/high density lipoprotein(TC/HDL)are correlated with ED.Studies have also shown that arterial stenosis and occlusion caused by hyperlipidemia could be attributed to the advanced-stage mechanism of ED induced by hyperlipidemia.Hyperlipidemia may damage man's erectile function at an early stage by affecting the endothelial cells and smooth muscles of the penis and the peripheral nerves for penile erection.Apart from dietary therapy and drug therapy aiming at hyperlipidemia,the traditional Chinese medicine therapy and gene therapy are two promising approaches to the treatment of ED caused by hyperlipidemia.