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颞叶低级别胶质瘤继发顽固性癫痫的外科治疗
引用本文:欧一博,舒凯,陈旭,董芳永,雷霆,李龄. 颞叶低级别胶质瘤继发顽固性癫痫的外科治疗[J]. 中国临床神经外科杂志, 2009, 14(4): 199-201
作者姓名:欧一博  舒凯  陈旭  董芳永  雷霆  李龄
作者单位:华中科技大学同济医学院附属同济医院神经外科,湖北武汉,430030
摘    要:目的探讨颞叶低级别胶质瘤继发顽固性癫痫患者的临床特点、术前评估及外科治疗效果。方法对31例颞叶低级别胶质瘤继发顽固性癫痫患者术前进行MRI、视频脑电图(VEEG)、发作间期正电子发射断层扫描(PET)检查,综合分析检查结果,制定相应手术方案。术中行皮层脑电描记(ECoG),术后对切除组织进行病理检查,并对患者进行术后随访。结果29例(93.5%)患者术后癫痫发作完全或部分缓解,2例(6.5%)患者无明显缓解。结论对于颞叶低级别胶质瘤继发顽固性癫痫的患者.术前进行综合评估,同时切除病灶及致痫灶是控制癫痫发作、改善预后的有效手段。

关 键 词:颞叶  低级别胶质瘤  顽固性癫痫  手术

Neurosurgery for Intractable Epilepsy Secondary to Temporal Low-grade Gliomas
Affiliation:OU Yi-bo, SHU Kai, CHEN Xu, et al.(Epilepsy Center, Department of Neurosurgery, Tongji Hospital, Tongji Medical School, Huazhong University of Sciences and Technology, Wuhan Hubei 430030, China)
Abstract:Objective To investigate the clinical features and surgical treatment of intractable epilepsy to temporal low-grade gliomas.Methods MRI,Video electroencephaolgram (EEC),position emission tomography(PET) were performed in 31 patients with intractable epilepsy secondary to temporal low-grade gliomas before the surgery.The operative plans were made according to the outcomes of the above-mentioned examinations. The gliomas and epileptogenic foci were resected by neurosurgery assisted by intraoperative electrocorticogram in all the patients,who were followed up for 3 months after the surgery.Results Of 31 patients,29 (93.5%)were completely or partly free of seizure and 2 (6.5%)were insignificantly improved in seizure after the surgery.Conclusions The detailed operative plans before the surgery according the outcome of MRI,Video EEG and PET examinations are mecessary to the sucdcessful resetion of the gliomas and epileptogenic foci,which is important to improvement of the prognoses in the patients with intractable secondary to temporal low-grade gliomas.
Keywords:Temporal lobe  Low-grade gliomas  Intractable epilepsy  Surgery
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