2004-2009年浙江省温州市急性弛缓性麻痹病例监测分析

目的了解浙江省温州市急性弛缓性麻痹(AFP)病例的流行特征,进一步提高AFP监测系统的敏感性、及时性、完整性,为制定保证无脊髓灰质炎状态的措施提供科学依据。方法对温州市2004-2009年AFP病例资料进行分析。结果 2004-2009年温州市共报告AFP病例100例,男女病例性别比为2.13∶1。发病率除2004年为0.5/10万外,其余年份在1/10万～1.5/10万之间,均保持在1/10万及以上。14 d内双份合格粪便标本采集率在95.2%～100%之间。除2008年随访率为76.5%,其余年份在87.5%～100%之间。此外AFP等监测指标均达到80%的要求。分离出4例脊灰病毒,均为疫苗株。结论温州市AFP各项监测指标明显提高,AFP监测工作日趋完善,因此做好脊髓灰质炎疫苗的常规免疫和强化免疫,提高AFP病例报告的敏感性和及时率,加强AFP管理的督导工作是继续保持无脊灰状态的重要保证。

Surveillance of acute flaccid paralysis in Wenzhou,Zhejiang province,2004-2009

Objective To understand the epidemiological characteristics of acute flaccid paralysis（AFP） in Wenzhou,improve the sensitivity,timeliness and completeness of AFP surveillance and provide evidences to keep polio-free status.Methods The data of AFP cases in Wenzhou during 2004-2009 were analyzed.Results A total of 100 AFP cases were reported and the ratio of male to female was 2.13∶1.The reported incidence of non-polio AFP cases was 0.5/lakh population15 years old in 2004,and it reached and remained above 1/lakh in the remaining yeas.The collection rate of two adequate stool specimens within 14 days of paralysis onset ranged from 95.2% to 100%.Four strains of polio virus were isolated which were all vaccine derivated poliovirus.The rate of follow-up was 76.5% in 2008 and ranged from 87.5% to 100% in the remaining years.All the other indictors of AFP surveillance reached the requirement of 80%.Conclusion All the indictors of AFP surveillance were improved.In order to maintain the polio-free status,it is important to conduct high level routine and supplementary immunization activities,improve the sensitivity and timeliness of AFP surveillance system and strengthen the supervision of AFP case management.