北京市东城区乙型病毒性肝炎血清流行病学调查

目的了解和分析北京市东城区1～59岁人群乙型病毒性肝炎(乙肝)病毒感染情况及乙肝疫苗免疫情况;探讨东城区乙肝病毒感染的影响因素;为制定防治策略提供参考。方法采用多阶段抽样方法,抽取东城区3个调查点1～59岁常住人口共593人,进行血清流行病学调查。结果东城区1～59岁人群乙肝病毒表面抗原(HBsAg)标化阳性率为4.57%,乙肝病毒核心抗体(抗-HBc)标化阳性率为26.03%;乙肝病毒表面抗体(抗-HBs)标化阳性率为44.88%,乙肝疫苗接种率为57.84%;≤14岁人群HBsAg阳性率为1.05%,抗-HBc阳性率为2.46%;抗-HBs阳性率为62.23%;乙肝疫苗接种率为97.54%;影响乙肝HBsAg阳性率的3大主要因素为家族中有无乙肝携带者、是否接种乙肝疫苗、是否经常去洗浴场所修脚。结论东城区在实施乙肝疫苗计划免疫管理后,人群乙肝携带率明显下降。

Seroepidemiological survey of hepatitis B in Dongcheng district,Beijing

Objective To determine the infection prevalence and immunization coverage of viral hepatitis B among the population aged from 1 to 59 in Dongcheng district,Beijing,and to identify the risk factors of the infection in this region,providing the basis for development of control strategies.Methods A multi-stage sampling method was used to carry out serological surveys for 593 resident subjects aged from 1 to 59 in Dongcheng district.Results For the surveyed population,the standardized seroprevalence of HBsAg,anti-HBc and anti-HBs was 4.57%,26.03% and 44.88%,respectively;the immunization coverage rate was 57.84%.For those aged 14 years or below,the seroprevalence of HBsAg,anti-HBc and anti-HBs was 1.05%,2.46% and 62.23%,respectively,with an immunization coverage rate of 97.54%.The three major risk factors for HBsAg positivity were the presence of a HBV-carrying family member,history of receiving HBV vaccines and frequent visits for pedicure bath.Conclusion After the implementation of the expanded program on immunization of HBV,the virus-carrying population in Dongcheng district reduced noticeably.