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帕利哌酮缓释片治疗老年精神分裂症30例
引用本文:张代江,吴胜.帕利哌酮缓释片治疗老年精神分裂症30例[J].中国药业,2013,22(5):82-83.
作者姓名:张代江  吴胜
作者单位:张代江 (重庆市精神卫生中心,重庆,401147); 吴胜 (重庆市精神卫生中心,重庆,401147);
摘    要:目的观察帕利哌酮治疗老年精神分裂症的疗效及安全性。方法对30例老年精神分裂症患者给予帕利哌酮治疗8周,采用阳性和阴性症状量表、不良反应量表评价疗效及不良反应。结果帕利哌酮具有良好的疗效,8周末显效率为60.00%,有效率为90.00%,不良反应主要为锥体外系反应、失眠、心动过速。结论帕利哌酮治疗老年精神分裂症疗效确切,不良反应少。

关 键 词:帕利哌酮  精神分裂症  老年

Paliperidone Extended- Release Tablets in Treating Senile Schizophrenia in 30 Case
Zhang Daijiang,Wu Sheng.Paliperidone Extended- Release Tablets in Treating Senile Schizophrenia in 30 Case[J].China Pharmaceuticals,2013,22(5):82-83.
Authors:Zhang Daijiang  Wu Sheng
Institution:( Chongqing Mental Health Center, Chongqing, China 401147)
Abstract:Objective To observe the effect and safety of paliperidone in treating senile schizophrenia. Methods Thirty senile schizophrenia patients were treated with paliperidone for 8 weeks. PANSS was used to evaluate the therapeutic effect and TESS was used to evaluate the drug side effects. Results Paliperidonehad satisfactory effect on senile schizophrenia, 90. 00% of the patients were improved,in which 60.00% improved significantly. The main side effects were EPS,insomina and tachycardia. Conclusion Paliperidone can effectively improve the symptoms of the senile schizophrenia,the side effects are mild,the safety of this product is good.
Keywords:paliperidone  schizophrenia  senile
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