舒利迭治疗慢性阻塞性肺疾病的临床观察

目的 探讨稳定期慢性阻塞性肺疾病(COPD)患者的有效治疗方法,以减少COPD的急性发作.方法 将32例COPD病人随机分为两组,实验组给予舒利迭50 μg～250 μg,1吸/次,2次/d治疗;对照组给予吸入异丙托溴铵50 μg,2次/d,并按需使用沙丁胺醇气雾剂治疗,疗程为6个月.在试验前后分别测定肺功能,并比较开...

Clinical Observation on COPD Treated with Seretide

Objective To investigate an effective treatment for chronic obstructive pulmonary disease(COPD) to lessen the acute attack of COPD.Methods 32 patients with COPD were randomly divided into two groups,the experimental group and the control groups,the experimental group was given seretide 50 μg~250 μg inhalation,twice daily;and the contfol group received the inhalation of Ipratropine 50 μg,twice per day,and the salbutamol aerosol was used once in need,6 months for one treatment cycle.Before and after treatment,the pulmonary function was tested.The acute attack times at 6 months before and after treatment in the two groups were all calculated.Results In the experimental gtoup,FEVl,FEVl/FVC and FEVl/predictive value were all increascd,compared to those before treatment,there were statistically significant differences,P<0.01;a decreased acute attack times at 6 months after treatment were found,compared to 6 months before treatment,P<0.01.In the control group,FEVl/FVC and FEVl/predictive value were almost the same,compared to those before trcatment,P>0.05;6 monrhs after treatmcnt,the acute attack times were,almost the same as those 6 months berore treatment,P>0.05.Conclusion Seretide could improve the pulmonary function of patients with COPO in stable period and lessen the acute attack times.