| rt-PA溶栓后早期抗血小板联合抗凝治疗维护神经功能的研究进展 |
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| 引用本文： | 叶琳琳,马学玲,李亮,李建堂,于元龙,王东伟,杨子超. rt-PA溶栓后早期抗血小板联合抗凝治疗维护神经功能的研究进展[J]. 黑龙江医学, 2011, 35(10): 741-744. DOI: 10.3969/j.issn.1004-5775.2011.10.008 |
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| 作者姓名： | 叶琳琳 马学玲 李亮 李建堂 于元龙 王东伟 杨子超 |
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| 作者单位： | 1. 哈尔滨医科大学附属第四医院神经科,黑龙江,哈尔滨,150001
2. 黑龙江省医院门诊部,黑龙江,哈尔滨,150001 |
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| 摘 要： | 急性缺血性卒中,是当今社会引起人类死亡和残疾的主要疾病.rt-PA为目前惟一批准用于治疗急性缺血性卒中的药物.然而,20%～34%的患者在溶栓后发生了再闭塞.而早期再闭塞与远期预后高度相关.本文通过溶栓后再闭塞的发生机制,综述溶栓后早期抗血小板联合抗凝治疗进行神经功能维护的研究进展.
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| 关 键 词： | 综述 缺血性卒中 再闭塞 溶栓 抗血小板 抗凝 |
The Progress of Early Antiplatelet and Anticoagulant Therapy after rt-PA Thrombolysis to maintain neurological function |
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| YE Lin-lin,MA Xue-ling,LI Liang,et al.. The Progress of Early Antiplatelet and Anticoagulant Therapy after rt-PA Thrombolysis to maintain neurological function[J]. Heilongjiang Medical Journal, 2011, 35(10): 741-744. DOI: 10.3969/j.issn.1004-5775.2011.10.008 |
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| Authors: | YE Lin-lin MA Xue-ling LI Liang et al. |
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| Affiliation: | YE Lin-lin,MA Xue-ling,LI Liang,et al.(Department of Neurology,the Fourth Affiliated Hospital of Harbin Medical University,Harbin 150001,CHINA) |
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| Abstract: | Acute ischemic stroke is an important cause of death and the most frequent cause of permanent disability recently.rt-PA is currently the only approved for the treatment of acute ischemic stroke thrombolytic drugs.However,re-occlusion occurs in 20~34% after rt-PA treated and early re-occlusion is highly predictive of long-term poor outcome.This review will discuss the rationale of ischemic stroke and potential therapeutic strategies after thrombolysis and the current situation of early antiplatelet and antic... |
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| Keywords: | Acute ischemic stroke Reocclusion Thrombolysis antiplatelet therapy Anticoagulant therapy |
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