乙型肝炎血清学指标阳性母亲哺乳问题的研究 |
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引用本文: | 杨晓 崔敏娴. 乙型肝炎血清学指标阳性母亲哺乳问题的研究[J]. 中华妇产科杂志, 1994, 29(10): 586-588 |
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作者姓名: | 杨晓 崔敏娴 |
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作者单位: | 杭州市妇幼保健院,杭州市中医医院,杭州市第六人民医院 |
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摘 要: | 检测61例乙型肝炎(乙肝)血清学指标阳性的母亲,初乳中乙型肝炎病毒(HBV)标志物及HBVDNA,分析从各类指标检出的阳性率与哺乳能否传播乙肝的相关性,并发现母血中传播性大的三项标志物为:乙型肝炎表面抗原(HBsAg)、乙型肝炎e抗原(HBeAg)及乙型肝炎核心抗体(抗-HBc),这几项标志物极易进入乳汁。而乙型肝炎表面抗体(抗-HBs)及乙型肝炎e抗体(抗-HBe)却不易进入乳汁。61份标本的HBVDNA阳性率(总排毒率)为42.6%。母血和初乳不同HBV标志物阳性组在相关的初乳中的排毒率呈高度一致性;母血中HBsAg、HBeAg、抗-HBc三项阳性、HBeAg及抗-HBc、HBsAg及抗-HBc、HBsAg及HBeAg和HBeAs阳性组初乳中的排毒率明显高于抗一HBs和(或)抗-口HBe阳性组。
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关 键 词: | 乳,人,乙型肝炎,脱氧核糖核酸 |
Study on breast-feeding by mothers with posi-tive serum hepatitis B virus test |
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Abstract: | ixty one samples of colostrum from mothers withpositive serum Hepatitis B virus(HBV)test were col-lected and determined for serial HBV markers alongwith HBVDNA.Results showed that HBsAg,HBeAgand anti-HBc were most likely transferred by milk,while anti-HBs and anti-HBe had less possibility toenter thecolostrum(P<0.01).The overall NBV DNApositive rate was 4 2.6%in the 61 samples.The variousHBV markers detected in mothers, serum presented ahigh consistency with those discovered in the corre-sponding milk samples. There were significantly higherrate of milk HBV transmission from mothers with serumpositive for HBsAg,HBeAg and anti-HBc or eitherone of them than those with positive for anti-HBs and/or anti-HBe. |
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Keywords: | Mik.human Hepatitis B DNA |
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