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卡托普利治疗高血压病短期与长期疗效的比较
引用本文:吴立荣 姚淙. 卡托普利治疗高血压病短期与长期疗效的比较[J]. 贵阳医学院学报, 1991, 16(2): 113-116
作者姓名:吴立荣 姚淙
作者单位:贵阳医学院附院心内科,贵阳医学院附院心内科,贵阳医学院附院心内科,贵阳医学院附院心内科,贵阳医学院附院心内科,贵阳医学院附院心内科
摘    要:本文应用卡托普利(Captopril,SQ14225)治疗高血压病短疗程组36例和长疗程组30例,总有效率分别为86.11%和76.67%,两组疗效无明显差异,而且长疗程组每日有效剂量显著低于短疗程组。两组治疗前后心率、血糖、血胆固醇、血尿酸、血肌酐、肝功能及血尿常规等检查均无明显变化。

关 键 词:卡托普利 高血压 疗效

Long-Term and Short-Term Effects of Captopril in Patients with Essential Hypertension
Wu Lirong,et al. Long-Term and Short-Term Effects of Captopril in Patients with Essential Hypertension[J]. Journal of Guiyang Medical College, 1991, 16(2): 113-116
Authors:Wu Lirong  et al
Affiliation:Wu Lirong,et al Department of Internal Medicine
Abstract:The long-term and short-term effects of captopril were compared in 66 patients with essential hypertension. The long-term group with 30 patients was treated for 4 weeks and the short-term group with 36 patients was treated for 12 to 36 months. The long-term and short-term groups had similar effects on the blood pressure and total response rates were 76. 67% and 86. 11%respectively. The effective daily doses of the long-term group were significantly lower than those of the short-term group. No serious side effects were observed and all the patients were well tolerated. Thus, captopril is one of the first-stage antihypertensive drugs for patients with essential hypertension during long-term.
Keywords:essential hypertension  captopril
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