| 声带白斑124例临床及病理分析 |
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| 引用本文： | 杨庆文,徐文,叶京英,王军,马丽晶,王小轶,魏洪政.声带白斑124例临床及病理分析[J].听力学及言语疾病杂志,2011,19(5):425-427. |
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| 作者姓名： | 杨庆文 徐文 叶京英 王军 马丽晶 王小轶 魏洪政 |
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| 作者单位： | 首都医科大学附属北京同仁医院耳鼻咽喉头颈外科中心(北京100730) |
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| 基金项目： | 北京市卫生系统高层次卫生技术人才骨干基金 |
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| 摘 要： | 目的探讨声带白斑的临床表现和病理特征及相关因素。方法回顾性分析2006年1月至2008年12月收治的124例声带白斑患者的临床资料,患者均于全身麻醉下行显微支撑喉镜下声带白斑切除术,术后切除的病变组织送病理检查。结果 124例声带白斑患者中,男120例,女4例;年龄29～84岁,平均49.65±10.13岁;有长期吸烟史者89例(71.77%,89/124),长期饮酒者67例(54.03%,67/124);双侧声带前中部病变75例(60.48%,75/124),单侧声带前中部病变29例(23.38%,29/124);病理检查显示:黏膜慢性炎症10例(8.06%),鳞状上皮增生88例(70.96%),黏膜轻度异型增生6例(4.84%),中度异型增生5例(4.03%),重度异型增生5例(4.03%),原位癌6例(4.84%),浸润癌4例(3.23%)。结论声带白斑以男性多见,长期烟酒嗜好可能是主要病因之一,其病变性质以病理诊断为依据,对病理检查提示有异型增生者需密切随诊观察。
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| 关 键 词： | 声带白斑 癌前病变 病理诊断 |
Clinical and Pathologlcal Analysis for 124 Cases of Vocal Cord Leukoplakia |
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| Yang Qingwen,Xu Wen,Ye Jingying,Wang Jun,Ma Lljing,Wang Xiaoyl,Wei Hongzheng.Clinical and Pathologlcal Analysis for 124 Cases of Vocal Cord Leukoplakia[J].Journal of Audiology and Speech Pathology,2011,19(5):425-427. |
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| Authors: | Yang Qingwen Xu Wen Ye Jingying Wang Jun Ma Lljing Wang Xiaoyl Wei Hongzheng |
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| Institution: | Yang Qingwen,Xu Wen,Ye Jingying,Wang Jun,Ma Lijing,Wang Xiaoyi,Wei Hongzheng[Department of Otolaryngology Head and Neck Surgery,Beijing Tongren Hospital,Capital Medical University,Key Laboratory of Otolaryngology Head and Neck Surgery(Capital Medical University),Ministry of Education,Capital Medical University),Beijing,100730,China] |
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| Abstract: | Objective To investigate the clinical and pathological features and related factors of vocal cord leukoplakis.Methods One hundred and twenty-four cases of vocal cord leukoplakia from January 2006 to December 2008 were analyzed.All the patients had undergone the surgery of vocal cord leukoplakia resection in retaining laryngoscope under general anesthesia with the specimens pathological examination.Results There were 120 males and 4 females in this study,the age ranged from 29 to 84 years,with the mean age o... |
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| Keywords: | Vocal cord leukoplakia Precancerous lesions Pathological diagnosis |
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