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药物性肝损伤临床分析
引用本文:丛春莉.药物性肝损伤临床分析[J].内蒙古医学杂志,2011,43(2):175-177.
作者姓名:丛春莉
作者单位:内蒙古医学院附属医院消化内科,内蒙古,呼和浩特,010050
摘    要:目的:研究药物性肝损伤病例的诊治情况,分析常见诱发药物及临床特点。方法:选择我院2006~2010年住院的药物性肝损伤患者54例,根据患者的病史、药物史、临床表现、肝功能及其他实验室检查结果,把导致肝损害的药物进行分类。54例患者中,其中男性31例,女性23例,年龄18~72岁,平均(50.1±16.9)岁。结果:药物性肝损伤病例中,急性肝细胞型占40.7%、淤胆型31.5%、混合型27.8%,绝大部分病人在停用相关的药物后能迅速恢复,对于一些特殊病例,特别是合并有其他肝脏疾病的患者,多有重症表现,死亡率高,导致肝损伤的药物中,抗结核药物占29.6%,中草药物占25.9%。结论:近几年药物性肝损伤病例逐渐增多,抗结核药物和中草药物是引起药物性肝损伤的重要原因。

关 键 词:肝脏疾病  药物  损伤

The Clinical Analysis with Drug Induced Liver Injury
CONG Chun-li.The Clinical Analysis with Drug Induced Liver Injury[J].Inner Mongolia Medical Journal,2011,43(2):175-177.
Authors:CONG Chun-li
Institution:CONG Chun-li(Department of Gastroenterology,The Affiliated Hospital of Inner Medical College,Huhhot 010050 China)
Abstract:Objective:To study and investigate the management of our hospital inpatients with drug induced liver injury(DILI),to evaluate the efficacy the drug and the clincal characteristics of DILI.in the treatment of the drug induced liver injury with acute cholestasis.Methods:From 2006 to 2010 in our hospital,54 patients with were diagnosed as DILI based on their medication history,clinical manifestation,liver function and other laboratory tests,the drugs suspected to induce liver injury were listed,in 54 patients ...
Keywords:Liver disease  Drug  Injury  
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