Gastroprotective activity of Camellia sinensis black tea brew in rats |
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| Authors: | Wanigasekera D. Ratnasooriya T. Saminda P. Fernando |
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| Affiliation: | 1. Department of Zoology, University of Colombo, Colombo, Sri Lankawdr@zoology.cmb.ac.lk;3. Department of Zoology, University of Colombo, Colombo, Sri Lanka |
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| Abstract: | This study examined the gastroprotective potential of a black tea brew (BTB) of Camellia sinensis Linn. O. Kuntze (Theaceae) using Sri Lankan high grown Dust grade No: 1 tea in a rat ethanol-induced gastric lesion model. Three oral doses of BTB (84, 167, or 501?mg/mL) were used in evaluation of the gastroprotective activity. The results showed a strong dose dependent and significant (p?C. sinensis possesses strong oral gastroprotective action, which is mediated via multiple mechanisms. The results also justify the claim made by Sri Lankan traditional practitioners that BTB of C. sinensis has gastroprotective action. |
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| Keywords: | Black tea Camellia sinensis gastroprotection gastric lesions |
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