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Antibacterial and Antifungal Activities of the Constituents of Flemingia paniculata. |
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| Authors: | M. Mukhlesur Rahman Alexander I. Gray Proma Khondkar Satyajit D. Sarker |
| Affiliation: | 1. Department of Pharmaceutical Sciences, University of Strathclyde, Glasgow, Scotland, UK;2. Department of Pharmacy, University of Rajshahi, Rajshahi, Bangladesh;3. Department of Pharmacy, University of Rajshahi, Rajshahi, Bangladesh;4. School of Biomedical Sciences, University of Ulster, Coleraine, Co. Londonderry, Northern Ireland, UK |
| Abstract: | AbstractA salicylic acid derivative (1), a cinnamaldehyde (2), and six isoflavones (3–8) from the stem bark of Flemingia paniculata. Wall. (Leguminosae) were tested for antibacterial (both Gram-positive and Gram-negative) and antifungal activities. All the compounds showed significant activities against the test organisms having MIC values in the range of 1.57–200 μ g/mL. The highest potency (MIC = 1.57 μ g/mL) was exhibited by 3 against Staphylococcus aureus.. |
| Keywords: | Antibacterial antifungal Flemingia paniculata Leguminosae |