Middle Cerebral Artery Circulation During Carotid Surgery: A Transcranial Doppler Study |
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Authors: | H Zachrisson D Jatuzis C Blomstrand J Holm R Volkmann |
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Institution: | 1. Department of Clinical Physiology, Sahlgrenska Unviersity Hospital, G?teborg, Sweden;2. Department of Surgery, Sahlgrenska Unviersity Hospital, G?teborg, Sweden;3. Department of Neurology, Sahlgrenska Unviersity Hospital, G?teborg, Sweden;4. Department of Neurology, Vilnius University Hospital, Lithuania |
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Abstract: | Objective - Perioperative carotid cross-clamping might induce low stump pressures as well as hypoperfusion of the middle cerebral artery. In this study blood flow velocities in the middle cerebral artery were compared with intraoperative measurements of the poststenotic carotid blood pressure. Design - Forty-one patients with internal carotid artery stenosis were operated on without shunting, under general anesthesia. Poststenotic carotid pressures and middle cerebral artery flow velocities were measured before and during cross-clamping. The hemodynamic responses to preoperative carotid compressions and intraoperative cross-clamping were evaluated. Results - In seven patients the poststenotic carotid blood pressure decreased on clamping despite unchanged or even increased middle cerebral artery blood flow velocities. In all other patients, pressure changes were significantly correlated to the decrease in middle cerebral artery blood flow velocities. Autoregulatory blood flow velocity responses after preoperative common carotid artery compression were not reproducible by cross-clamping. Conclusions - Stump blood pressure measurements may not reflect middle cerebral artery perfusion in about 20% of thrombendarterectomies performed under general anesthesia. A possible explanation might be dimished cerebral autoregulation and changes in collateral flow distributions. |
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Keywords: | Carotid Artery Stenosis Middle Cerebral Artery Blood Flow Stump Blood Pressure Thrombendarterectomy Transcranial Doppler |
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