Antiulcerogenic Activity of Alhagi maurorum. |
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| Authors: | AS Awaad Amani DJ Maitland GA Soliman |
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| Institution: | 1. Aromatic and Medicinal Plant Department, Desert Research Center, Cairo, Egypt;2. Chemistry and Forensic Medicine Department, School of Life Science, Bradford University, Bradford, United Kingdom;3. Pharmacology Department, Faculty of Veterinary Medicine, Cairo University, Cairo, Egypt |
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| Abstract: | AbstractSix main flavonoid glycosides were isolated, for the first time, from the ethanol extract of Alhagi maurorum Boiss (Leguminosae).. They were identified as kaempferol, chrysoeriol, isorhamnetin, chrysoeriol-7-O.-xylosoid, kaempferol-3-galactorhamnoside, and isorhamnetin 3-O.-β-D-apio-furanosyl (1-2) β-D-galactopyranoside. Their identities were established by m.p., UV, EI-mass, Fab-mass, 600 MHz 1H and 13C NMR. The total extract (300 and 400 mg/kg) and two of the isolated compounds (chrysoeriol 7-O.-xylosoid and kaempferol-3-galactorhamnoside, 100 mg/kg each) showed a very promising antiulcerogenic activity with curative ratios 66.31%, 69.57%, 75.49%, and 77.93%, respectively. |
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| Keywords: | Alhagi maurorum antiulcerogenic activity chrysoeriol-7-O -xylosoidflavonoids isorhamnetin kaempferol-3-galactorhamnoside |
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