| 光纤药物溶出度实时测定仪考察头孢克洛胶囊溶出曲线 |
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| 引用本文： | 倪明,郑悦,刘成红,罗晓茹,吴艳,田增光,魏立平. 光纤药物溶出度实时测定仪考察头孢克洛胶囊溶出曲线[J]. 解放军药学学报, 2013, 0(2): 144-145 |
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| 作者姓名： | 倪明 郑悦 刘成红 罗晓茹 吴艳 田增光 魏立平 |
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| 作者单位： | 总后勤部卫生部药品仪器检验所,北京100166 |
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| 摘 要： | 目的考察头孢克洛胶囊溶出曲线,评价其内在质量。方法用光纤溶出度实时测定仪实时测定头孢克洛胶囊的溶出曲线,篮法100 r·min-1,溶出介质为900 ml水。结果 6个生产企业样品均在15 min溶出85%以上。结论 6个生产企业头孢克洛胶囊溶出度内在质量较好。
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| 关 键 词： | 光纤药物溶出度实时测定法 头孢克洛胶囊 溶出度 |
Dissolution Curves of Cefaclor Capsules by Fiber-optic Medicine Dissolution Real Time Test System |
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| NI Ming,ZHENG Yue,LIU Cheng-hong,LUO Xiao-ru,WU Yan,TIAN Zeng-guang,WEI Li-ping. Dissolution Curves of Cefaclor Capsules by Fiber-optic Medicine Dissolution Real Time Test System[J]. Pharmaceutical Journal of Chinese People's Liberation Army, 2013, 0(2): 144-145 |
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| Authors: | NI Ming ZHENG Yue LIU Cheng-hong LUO Xiao-ru WU Yan TIAN Zeng-guang WEI Li-ping |
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| Affiliation: | Institute for Drug and Instrument Control, Health Dept, GLD of PLA, Beijing 100166, China |
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| Abstract: | Objective To investigate the dissolution curves of cefaclor capsules and evaluate their intrinsic quality. Methods The dissolution curves of cefaclor capsules were determined by the fiber-optic medicine dissolution real time test system with 900 ml water as the menstruum. The speed of the rotating basket was 100 r min-1. Re- suits The dissolutions of six samples from six manufacturers were all up to 85% in 15 minutes. Conclusion Cefaclor capsules from six manufacturers have satisfactory dissolution curves and prove to be of good quality. |
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| Keywords: | fiber-optic dissolution process real time test cefaclor capsules dissolution |
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