创面敷料封闭负压引流治疗慢性创面

背景：前期研究发现采用生物材料创面敷料封闭负压引流装置治疗创面后期由于局部创面的血污、组织分泌物或细菌滋生原因会出现堵管,而堵管区域下方的软组织修复往往不能获得满意效果. 目的：观察采用间隙冲洗式生物材料创面敷料封闭负压引流治疗慢性创面的临床效果. 方法：36例慢性创面患者采取自愿选择治疗的方式,分为间隙冲洗式生物材料创面敷料封闭负压引流、合成敷料封闭负压引流、常规换药处理治疗. 结果与结论：与合成敷料封闭负压引流组及常规换药处理组比较,间隙冲洗式生物材料创面敷料封闭负压引流组创面细菌检出率明显降低（P〈0.05）,愈合时间明显缩短（P〈0.05）;间隙冲洗式生物材料创面敷料封闭负压引流组治疗期间疼痛目测类比评分明显优于常规换药组（P 〈0.05）,与合成敷料封闭负压引流组比较差异无显著性意义（P 〉0.05）.提示采用间隙冲洗式生物材料创面敷料封闭负压引流能有效促进慢性创面愈合,降低创面感染率,减轻患者治疗时的痛苦,且无不良反应.

Application of clearance flush vacuum-sealing drainage based on wound dressing in chronic wounds

BACKGROUND：Preliminary studies have found that local wound gory, tissue secretions or bacteria growth can result in tube jam after treatment with vacuum-sealing drainage based on biomaterial wound surface dressing, and we cannot get satisfied results in the repair of soft tissues below the blocked tube area. OBJECTIVE：To study the curative effect of clearance flush vacuum-sealing drainage based on biomaterial dressing in the treatment of chronic wounds. METHODS：Thirty-six patients with chronic wounds were divided into three groups which were cured by clearance flush vacuum-sealing drainage based on biomaterial dressing, vacuum-sealing drainage based on synthetic dressing and conventional dressings by their wil ingness. RESULTS AND CONCLUSION：The bacteria detection rate of clearance flush vacuum-sealing drainage based on biomaterial wound surface dressing group was inferior to the synthetic dressing group and conventional dressing group （P〈0.05）. And the healing time was shorter in the former one group （P〈0.05）. The score on the visual analogue pain in the clearance flush vacuum-sealing drainage based on biomaterial wound surface dressing group was better than that in the conventional dressing group （P〈0.05）, but did not significantly differ from that in the synthetic dressing group （P〉0.05）. These findings indicate that clearance flush vacuum-sealing drainage based on biomaterial wound surface dressing can promote chronic wound healing, reduce the wound infection rate, relieve the pain of patients when treatment, and have no adverse.