CO_2气腹对家兔糖代谢的影响

目的：观察不同压力CO2气腹对家兔糖代谢的影响。方法：健康家兔20只，随机分为4组，每组5只，分别给予1h不同压力的CO2气腹：对照组0mmHg、A组10mmHg、B组15mmHg、C组20mmHg。于气腹前、气腹30min、60min、4h、24h采集股静脉血，测定血糖、胰岛素、C-肽、乳酸。结果：CO2气腹后各组血糖均升高，气腹压力越大，血糖升高的速度越快，峰值越高。对照组、A组胰岛素和C-肽气腹前后无明显变化，B、C组较气腹前明显升高；各组乳酸浓度无明显变化；CO2气腹后胰岛素敏感指数（ISI）在B、C组明显降低，且气腹压力越高，ISI降低越明显。结论：结果表明CO2气腹可引起血糖、胰岛素升高，胰岛素敏感性降低，产生胰岛素抵抗（IR），且程度与CO2气腹压力有关。

Effects of CO_2 pneumoperitoneum on glycometabolism in rabbits

Objective:To observe the effects of CO2 pneumoperitoneum on glycometabolism in rabbits.Methods:20 healthy rabbits were divided randomly into four groups and each group had five rabbits. CO2 pneumoperitoneum at different pressure was established for 1 h. The pressure of CO2 pneumoperitoneum was 0 mmHg in the control group, 10 mmHg in group A, 15 mmHg in group B, 20 mmHg in group C. The levels of plasma glucose, insulin, C-peptide, lactic acid were measured before and in 30 min, 1 h, 4 h and 24 h after the pn...