老年人脑卒中后痴呆危险因素分析

目的　探讨老年人脑卒中后痴呆的危险因素。方法　对 2 5 8例资料完整的老年脑卒中患者进行了 3个月随访评价 ,包括临床神经学和神经心理学测试 ,对研究资料先进行单因素分析 ,然后进行多因素非条件Lo gistic回归模型分析。 结果　脑卒中后痴呆发生率为 32 2 %。经分析筛选出多灶病变、左侧及双侧病变、脑萎缩、年龄、高血压、以往脑血管病病史、大面积出血或梗死 8个因素为脑卒中后痴呆危险因素。结论　老年人脑卒中后痴呆由多种因素决定 ,它不仅与病灶部位、数目、大小及发病次数有关 ,亦与脑卒中患者基础脑功能状态有关。

Analysis of risk factors of dementia after stroke in elderly patients

Objective To explore the risk factors of dementia induced by stroke.Methods 258 elder patients with stroke had been followed up for three months,including clinical neuropathy and neuropsychological tests.Multivariate noncondition stepwise Logistic model analysis was made after single variable analysis.Results There were 83 patients with dementia induced by stroke,175 patients without dementia after stroke.The morbidity was 32.2%.The following eight factors were associated with dementia i.e.,age,multiple lesions,left lesion,large area of cerebral hemorrhage or cerebral infarction,cerebral atrophy,hypertension,the history of stroke,and bilateral lesions.Conclusions Dementia induced by stroke is caused by multiple factors.It is closely correlated to numbers of cerebral lesions,the location of cerebral lesions and the size of brain tissue necrosis.The primary conditions of patients'cerebral function are also closely associated with the occurence of dementia.