南宁地区孕妇TORCH感染的检测与分析

目的探讨南宁地区孕妇感染TORCH刚地弓形虫(toxoplasma gondii,TOX)、风疹病毒(rubella virus,RV)、巨细胞病毒(cytomegalovirus,CMV)、单纯性疱疹病毒(herpes simplex virus,HSV)]检出率,做好优生优育并为临床医生提供实验依据。方法对广西壮族自治区妇产医院2014年1~2月2 155例孕妇采用酶联免疫吸附实验(enzyme-linked immunosorbent assay,ELISA)法检测血清中特异性TORCH-IgM进行分析,同时对其中978例进行TORCH-IgG抗体检测,对350例有不良孕产史的孕妇和1 805例正常妊娠孕妇的检测结果进行比较。结果检测发现TORCH-IgM总阳性率为7.61%,其中CMV-IgM、TOX-IgM、RV-IgM、HSV1-IgM、HSV2-IgM阳性率分别为2.01%、1.11%、1.62%、1.48%、1.30%。TOX-IgG、RVIgG、CMV-IgG、HSV1-IgG、HSV2-IgG阳性率分别为4.60%、89.2%、94.9%、87.8%、14.4%。有不良孕产史孕妇血清TORCH-IgM总阳性率为14.57%,高于正常妊娠孕妇(P0.05)。结论 TORCH感染导致不良妊娠结局,应加强对育龄妇女孕前和孕期TORCH筛查。

Detection and analysis of pregnant women TORCH infection in Nanning region

Objective To investigate the detection rate of TORCH infection （ toxoplasma gondii, rubella virus, cytomegalovirus, herpes simplex virus ） in pregnant women in Nanning region and to provide experimental basis to clinicians for eugenics. Methods 2 155 pregnant women in Gynecology and Obstetrics Hospital of Guangxi Zhuang Autonomous Region from January 2014 to February 2014 were detected TORCH - IgM using ELISA, in which 978 cases were detected TORCH - lgG. The detection results of 350 cases with abnormal pregnancy history and 1 805 cases with normal pregnancy were compared. Results The total positive rate of TORCH - IgM was 7.61% , positive rate of CMV - IgM, TOX - IgM, RV - IgM, HSV1 - IgM, HSV2 - IgM were 2. 01%, 1.11%, 1.62%, 1.48%, 1.30% respectively. The positive rate of TOX - IgG, RV - IgG, CMV - IgG, HSV2 - lgG, HSV1 - IgG were 4. 60% , 89.2% , 94. 9% , 87.8% , 14.4% respectively. Positive rate of TORCH - IgM in pregnancy women withabnormal pregnancy history was 14. 57% , which was higher than that of normal pregnancy （P 〈 0. 05 ）. Conclusion TORCH infection is an important cause of adverse pregnancy outcomes, therefore TORCH detection should be strengthened in women of child - bearing age