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复方果糖电解质注射液在骨创伤患者中的疗效观察
引用本文:李雨虹,杨素霞,孙璟川,陈宇童,李烟花,濮世俊,季美丽,朱有华,隋明星. 复方果糖电解质注射液在骨创伤患者中的疗效观察[J]. 第二军医大学学报, 2022, 43(7): 772-777
作者姓名:李雨虹  杨素霞  孙璟川  陈宇童  李烟花  濮世俊  季美丽  朱有华  隋明星
作者单位:海军军医大学(第二军医大学)第一附属医院器官移植科,上海 200433;海军军医大学(第二军医大学)第二附属医院骨科,上海 200003
基金项目:全军医学科技青年培训计划应用基础研究项目(21QNY041),海军军医大学(第二军医大学)第一附属医院“深蓝123”军事医学研究专项探索培育项目(2020SLZ007).
摘    要:目的 探讨复方果糖电解质注射液在骨创伤患者中的临床疗效和应用价值。方法 选取2020年1月到2021年6月在我院行骨创伤切开复位内固定术的患者80例,随机分为对照组和试验组,每组各40例。对照组予5%葡萄糖注射液2000ml/日,注射液中添加1.5g氯化钾和1g葡萄糖酸钙,连续补液治疗5天;试验组予复方果糖电解质注射液2000ml/日,连续补液治疗5天,观察两组患者的血糖、肝肾功能、电解质、血液流变学及伤口愈合情况。结果 术后所有患者生命体征平稳。对照组血糖水平明显高于试验组(P <0.01),并且对照组的血糖水平波动幅度较大。两组血液流变学和凝血功能差异具有显著的统计学意义(P <0.05),但两组电解质、肝肾功能无显著差异。结论 复方果糖电解质注射液可以安全应用于骨创伤患者,对患者的血糖、肝肾功能和电解质等影响较小,又可以降低血液粘滞度,相对而言血栓风险更低,补液简洁、方便、安全。

关 键 词:复方果糖电解质注射液  骨创伤  血糖  电解质  血液流变学
收稿时间:2021-10-09
修稿时间:2022-06-29

Compound fructose electrolyte injection in patients with bone trauma:efficacy observation
LI Yu-hong,YANG Su-xi,SUN Jing-chuan,CHEN Yu-tong,LI Yan-hu,PU Shi-jun,JI Mei-li,ZHU You-hu,SUI Ming-xing. Compound fructose electrolyte injection in patients with bone trauma:efficacy observation[J]. Former Academic Journal of Second Military Medical University, 2022, 43(7): 772-777
Authors:LI Yu-hong  YANG Su-xi  SUN Jing-chuan  CHEN Yu-tong  LI Yan-hu  PU Shi-jun  JI Mei-li  ZHU You-hu  SUI Ming-xing
Affiliation:Department of Organ Transplantation, Changhai Hospital,
Abstract:Objective: to investigate the clinical efficacy and application value of compound fructose electrolyte injection in patients with bone trauma. Methods: 80 patients who underwent open reduction and internal fixation of bone trauma in our hospital from January 2020 to June 2021 were randomly divided into control group (n = 40) and experimental group (n = 40). The control group was given 5% glucose injection 2000ml/ day, 1.5 g potassium chloride and 1 g calcium gluconate were added to the injection for 5 days, and the experimental group was treated with compound fructose electrolyte injection 2000ml/ day for 5 days. The blood glucose, liver and kidney function, electrolyte, hemorheology and wound healing of the two groups were observed. Results: the vital signs of all patients were stable after operation. The blood glucose level in the control group was significantly higher than that in the experimental group (P < 0.01), and the blood glucose level in the control group fluctuated greatly. There were significant differences in hemorheology and coagulation function between the two groups (P < 0.05), but there was no significant difference in electrolyte, liver and kidney function between the two groups. Conclusion: compound fructose electrolyte injection can be safely used in patients with bone trauma with little effect on blood glucose, liver and kidney function and electrolytes, and can reduce blood viscosity. Relatively speaking, the risk of thrombosis is lower. Fluid replacement is simple, convenient and safe.
Keywords:Compound fructose electrolyte   Bone trauma   Blood glucose   electrolyte   Hemorheology
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