迟发性维生素K缺乏性颅内出血临床分析

目的总结迟发性维生素K缺乏性颅内出血的诱因及临床表现等,做到对该病的早防早治.方法对我院32例因该病入院的患儿的临床资料、诱因、治疗及预后进行分析.结果 16例(50%)患儿起病前有发热、腹泻等感染病史.单纯母乳喂养儿25例占78.1%.全部病例维生素K治疗有效,留有神经系统后遗症者8例占23.8%,死亡4例占12.9%.结论迟发性维生素K缺乏性颅内出血是新生儿晚期至3个月内婴儿常见疾病,该病致残率、死亡率较高,要做到早防早治,尤其是预防性应用维生素K可以减少和避免此病的发生.

Clinical analysis for delayed Vitamin K deficiency intracranial hemorrhage

Objective To summarize the inducement and clinical manifestations of delayed Vitamin K deficiency intracranial hemorrhage,for earlier diagnose,treatment and prevention the disease.Methods To analyze 32 cases of delayed Vitamin K deficiency intracranial hemorrhage including clinical manifestation,inducement,therapy and prognosis.Results 16 cases(50%) suffered from fever or/and diarrhea.25 cases(78.1%) were only fed by breast feeding.Vitamin K was effective to all of the cases.23.8%(8/32) had sequelae of nerve system,4 cases were dead accounting for 12.9%.Conclusion The delayed Vitamin K deficiency intracranial hemorrhage often occurs at late period of neonate and infants within 3 month,which may cause more functional disorders and higher mortality.(Preventive) application of Vitamin K could decrease or avoid the occurrence of the disease.