| HPLC法测定天麻胶囊中天麻素的含量 |
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| 引用本文： | 赵红丹,王巍,宋妍羲,林长旭,鞠成国. HPLC法测定天麻胶囊中天麻素的含量[J]. 辽宁中医学院学报, 2011, 0(5): 246-247 |
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| 作者姓名： | 赵红丹 王巍 宋妍羲 林长旭 鞠成国 |
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| 作者单位： | [1]沈阳双鼎制药有限公司,辽宁沈阳110179 [2]辽宁中医药大学,辽宁大连116600 |
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| 摘 要： | 目的：建立天麻胶囊中天麻素的含量测定方法。方法：采用Agilent 1100液相色谱仪,Diamonsil TMC18柱（200mm×4.6mm）,流动相为乙腈-0.5%磷酸水溶液（2∶98）,流速1.0mL/min,检测波长222nm,柱温30℃。结果：天麻素在0.0186-0.2011μg范围内线性关系良好,r=0.9999,平均回收率为98.4%,RSD=0.68（n=6）。结论：该法简便快速,结果准确,重现性好,可作为该制剂的质量控制方法。
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| 关 键 词： | 天麻胶囊 高效液相色谱法 天麻素 |
Determination of Gastrodin in Tianma Capsule by HPLC |
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| ZHAO Hong-dan,WANG Wei,SONG Yan-xi,LIN Chang-xu,JU Cheng-guo. Determination of Gastrodin in Tianma Capsule by HPLC[J]. Journal of Liaoning College of Traditional Chinese Medicine, 2011, 0(5): 246-247 |
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| Authors: | ZHAO Hong-dan WANG Wei SONG Yan-xi LIN Chang-xu JU Cheng-guo |
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| Affiliation: | 1.Shenyang Shuangding Pharmaceutical Co.Ltd.,Shenyang 110179,Liaoning,China;2.Liaoning University of Traditional Chinese Medicine,Dalian 116600,Liaoning,China) |
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| Abstract: | Objective：To determine Gastrodin in Tianma capsule.Methods：Agilent 1100 HPLC,Diamonsil TM C18 column（200mm×4.6mm）was eluted,the mobile phase consisted of acetonitrile-0.5% phosphoric acid at the column temperature 30℃.The flow rate was 1.0mL/min and detective wavelength was 222nm.Results：Gastrodin was proved to be linear in the range of 1.86~20.11μg with a regression coefficient of 0.9999.The average recovery was 98.4%（n=6,RSD=0.68%）.Conclusion：This method was sensitive,quick and accurate for the quantity control of this preparation. |
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| Keywords: | Tianma capsule HPLC Gastrodin |
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