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Dystonia gravidarum: A new entity?
Authors:Erle Chuen-Hian Lim  Raymond Chee-Seong Seet  Einar P V Wilder-Smith  Benjamin Kian-Chung Ong
Affiliation:Division of Neurology, National University Hospital, Singapore. mdcelch@nus.edu.sg
Abstract:We describe cervical dystonia occurring in a 31-year-old, previously well, primigravid, primiparous Chinese woman at 4 weeks' amenorrhea, which was ameliorated with low-dose clonazepam and disappeared completely by the end of the second trimester without recurring despite her being tapered off benzodiazepine therapy. Investigations were unremarkable for structural and biochemical causes of dystonia. Chorea, paraballismus, and restless legs syndrome are known to occur during pregnancy, attributable to high estrogen levels. Dystonia, on the other hand, has not been described to occur de novo in pregnancy. This association should be considered in women of reproductive age who present with cervical dystonia.
Keywords:dystonia  gravidarum  pregnancy  estrogen  oculogyric crisis
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