75例卵巢交界性上皮性肿瘤的诊治及预后分析

目的探讨卵巢交界性上皮肿瘤的临床特点、诊治方法及相关预后。方法回顾性分析75例卵巢交界性上皮性肿瘤的临床资料。结果 75例患者中,平均发病年龄为(45.3±3.5)岁;病理分类为浆液性35例,黏液性39例,子宫内膜样1例;单侧72例,双侧3例;结合术后病理检查临床分期为Ⅰ期56例(其中Ⅰa期33例),Ⅱ期9例,Ⅲ期10例;患者均行手术治疗,部分患者(19例)辅助以化疗(CP或PAC方案);随访患者69例,其中复发2例,死亡1例。结论卵巢交界性上皮性肿瘤预后良好,手术是其主要的治疗方式,对于早期有生育要求的患者可选择保守性手术,力求将肿瘤完全切除,晚期患者应行根治性手术;患者术后可辅助化疗,并积极随访,可提高患者生存率。

Borderline ovarian tumor:a clinical analysis of 75 cases

Objective To explore the clinical features and management of borderline ovarian tumor （BOT）. Methods Seventy-five cases with BOT were analyzed retrospectively. Results The average age of the patients was 45.3 years. Pathological type included 35 cases of serious tumor,39 cases of mucous tumor, 1 case of endometrioid tumor. 72 cases were unilateral,3 cases bilateral. All the patients accepted surgical treatment ,56 cases of which were in surgical-pathologic stage I ,9 cases stage I1,10 cases stage llI. A part of those（ 19 cases） received postoperative chemotherapy. One case died among 69 cases followed up to the end. There were two cases relapsed. Conclusion BOT appears to have a favorable prognosis, and surgery is the proved only effective treatment for BOT till now. Conservative surgery is proper treatment for young patients having fertility requirements. The terminally ill should be taken radical surgery, and received postoperative chemotherapy. We should make an active following-up mechanism to improve the survival rate of patients.