颞叶脑梗死患者的决策认知障碍

目的探讨颞叶脑梗死(TLCI)患者的社会决策认知能力。方法将15例TLCI患者以及20例与其人口学资料相匹配的健康人作为被试,采用爱荷华博弈任务(iowa gambling task)对上述两组进行社会决策行为能力的测试。结果与正常对照组相比,TLCI患者不仅存在数字广度及执行功能障碍,还存在决策认知障碍。在博弈任务中有利选择的次数以及金钱总收益明显减少,差异有统计学意义(P0.05)。随着博弈任务卡片选择数的增多,正常对照组逐渐倾向于对自己有利的选择;而TLCI患者却不具有这种决策模式。结论 TLCI患者存在决策认知功能障碍,提示颞叶可能参与了人类的决策认知加工过程。

Deficit of decision-making in patients with temporal lobe cerebral infarction

Objective To investigate the ability of decision making in patients with temporal lobe cerebral infarction.Methods Fifteen patients with temporal lobe cerebral infarction（TLCI） and twenty healthy controls（HC） were examined with the Iowa gambling task（IGT） to assess decision making based on feedback processing.Results The result showed that TLCI group impaired not only on the subcomponent of executive task but also decision making on the IGT compared with the HC group.In Iowa gambling task,the TLCI group selected less advantageous cards and less total amount of gained money than health controls（P0.05）.The study indicated that the health controls gradually shifted their selections toward the good decks as the game progressed,but the TLCI group did not exhibit this advantageous shift in decision making.Conclusion The present study suggests that the decision making impairment is in patients with TLCI,and indicates that temporal lobe might be involved in decision making processes.