咪唑安定与氟芬合剂辅助椎管内麻醉的镇静效果比较

[目的 ]探讨咪唑安定 (Midazolam ,M )与氟芬 (DF)合剂辅助椎管内麻醉的镇静效果。 [方法 ]90例下腹部手术椎管内麻醉患者 ,随机分为 3组 (A ,B ,C组 )各 30例。A组静注M同时肌注DF ;B组肌注M DF ,C组仅肌注DF。注药后不同时段记录镇静情况 ,以Ramsay改良法 (Berggren)行镇静深度分级 ,观察RR、SPO2 、HR、BP及术中牵拉反应次数。 [结果 ]注药后 15min ,A组达镇静2级者较B、C两组显著增多 (P <0 0 5 ) ;B组达镇静 2级者也较C组显著增多 (P <0 .0 5 )。75min3组镇静水平基本相同。A、B两组在围术期对牵拉反应、刺激回忆显著少于C组。 [结论 ]咪唑安定静注或肌注伍用氟芬合剂辅助镇静 ,能迅速加深镇静深度 ,减少疼痛、牵拉反应不良回忆。

Clinical study of midazolam and roperidol-fentanyl under epidural anesthesia

Objective Clinical study of midazolam and droperidol-fentanyl under epidural anesthesia. [Methods] Of 90 patients were divided randomly into 3 groups(n=30). Group A received midazolam i.v and droperidol-fentanyl i .m; Group B was received midazolam droperidol-fentanyl i.m; Group c received droperidol-fentanyl i.m. [Result] The group A have significant better sedative action than the group B,P<0.05. The group B also have significant better sedative action than the group C,P<0.05 . Both the group A and the group B have significant better decrease entrails pain than the group C,P<0.05. [Conclusions] Droperidol-fentanyl complied with midazolam i.v or i.m can increase sedative action,decrease entrails pain , have no significant influence on haemodynamic and respiratory under epidural anesthesia.