| 大鼠慢性萎缩性胃炎脾胃虚寒型模型建立的实验研究 |
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| 引用本文： | 杨建辉,张峰. 大鼠慢性萎缩性胃炎脾胃虚寒型模型建立的实验研究[J]. 江西中医学院学报, 2012, 24(3): 66-69 |
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| 作者姓名： | 杨建辉 张峰 |
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| 作者单位： | 1. 广东省河源市人民医院内四科 河源517000
2. 陕西中医学院 咸阳712046 |
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| 摘 要： | 目的:建立慢性萎缩性胃炎脾胃虚寒型的大鼠动物模型.方法 50只大鼠随机分为空白组、氨水对照组、乙醇对照组、综合法造模组,经过不同方法造模后,比较各种造模方法的模型建立效果.结果 综合法造模组大鼠在一般形态、体重变化方面与对照组无明显差别,但在胃粘膜病理组织特点方面,较对照组成功,基本符合慢性萎缩性胃炎病理特点.结论 采用综合法建立大鼠慢性萎缩性胃炎脾胃虚寒型动物模型是一种操作简单、成功率高的造模方法.
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| 关 键 词： | 慢性萎缩性胃炎 脾胃虚寒型 动物模型 实验研究 |
Study in Rats Model with Chronic Atrophic Gastritis of Spleen and Stomach Cold of Insufficiency Type |
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| YANG Jian-hui , ZHANG Feng. Study in Rats Model with Chronic Atrophic Gastritis of Spleen and Stomach Cold of Insufficiency Type[J]. Journal of Jiangxi College of Traditional Chinese Medicine, 2012, 24(3): 66-69 |
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| Authors: | YANG Jian-hui ZHANG Feng |
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| Affiliation: | 1.The People’s Hospital of Heyuan City,Guangdong Heyuan,517000;2.Shaanxi University of Chinese Medicine,Shaanxi Xi’an,712046 |
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| Abstract: | Objective: To make the rat model of chronic atrophic gastritis of spleen and stomach cold of insufficiency type.Methods: 50 rats were randomly divided into the blank control group,ammonia control group,ethanol control group and comprehensive method group,using different methods to make models,to comparison of the different effects on models.Results: Comprehensive method group com pared with the control group,had no significant difference in the general form and weight change,but comprehensive method group bet ter than the control group in pathology of gastric mucosa,basically consistent with chronic atrophic gastritis pathological characteristics.Conclusion:The comprehensive method in making rat model of chronic atrophic gastritis of spleen and stomach cold of insufficiency type,is a kind of simple operation and high success rate of molding method. |
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| Keywords: | Chronic atrophic gastritis Spleen and stomach cold of insufficiency type Rat model Experimental study |
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