正常孕妇早-中孕期子宫动脉血流阻力参数的序贯研究

目的探讨正常孕妇孕早期至孕中期子宫动脉血流参数的变化规律，为相关疾病的预测提供依据。方法孕11～14 周及孕18～20 周超声分别检测双侧子宫动脉搏动指数（PI）、阻力指数（RI），观察上述指标在早孕- 中孕的变化情况。结果正常孕妇左侧子宫动脉PI、RI 早孕期分别为（1.56±0.518）及（0.71±0.112），中孕期降至（1.13±0.424）及（0.61±0.109），右侧子宫动脉PI、RI 早孕期（1.50±0.518）、（0.70±0.106），中孕期降至（1.01±0.391）、（0.57±0.117）。子宫动脉阻力参数PI、RI 早孕期与中孕期比较差异有统计学意义（P <0.05），孕11～14 周子宫动脉阻力参数左右两侧比较差异无统计学意义（P >0.05），孕18～20 周子宫动脉阻力参数两侧比较差异有统计学意义（P <0.05）。结论从早孕期至中孕期，正常孕妇子宫动脉阻力参数下降。

Sequential research on uterine artery blood flow resistance parameters in early-middle pregnancy of normal pregnant women

Objective To detect the change rule of uterine artery blood flow resistance parameter in early-middle pregnancy of normal pregnant women, and provide the basis to the prediction of related diseases. Methods The resistance index (RI) and pulsation index (PI) of uterine artery on both sides of the normal pregnant women at 11-14 weeks and 18-20 weeks of gestation were detected, and the change rule of these parameters in the process of early to middle pregnancy was observed. Results PI of the left side uterine artery was (1.56 ±0.518) in the early pregnancy, and reduced to (1.13 ±0.424) in the middle pregnancy. RI of the left side uterine artery reduced from (0.71 ±0.112) to (0.61 ±0.109). PI of the right side uterine artery was (1.50 ±0.518), and reduced to (1.01 ±0.391) in the middle pregnancy. RI of the right side uterine artery reduced from (0.70 ±0.106) to (0.59 ±0.114). There were significant differences in uterine artery blood flow resistance parameters (PI and RI) between early pregnancy and middle pregnancy (P < 0.05). The uterine artery blood flow resistance parameters (PI and RI) had no significantly different between left and right sides at early pregnancy (P > 0.05), but had significantly different in middle pregnancy (P < 0.05). Conclusions The uterine artery blood flow resistance parameters are significantly reduced from early pregnancy to middle pregnancy.