角膜绷带镜固定角膜缘干细胞移植片在原发性翼状胬肉切除术中的应用

目的：评估无缝线角膜绷带镜固定角膜缘干细胞移植片法在原发性翼状胬肉切除术中的应用效果。

方法：选取我院于2019-01/12收治的双眼原发性翼状胬肉患者25例50眼进行前瞻性临床研究，术中随机对每位患者其中1眼采用无缝线角膜绷带镜固定角膜缘干细胞移植片(A组，25眼)，另1眼采用传统缝线法固定角膜缘干细胞移植片(B组，25眼)。记录两组患眼手术时间，术后随访6mo，观察两组患眼舒适感、移植物固定稳定性、并发症及复发情况。

结果：A组平均手术时间(13.5±2.1min)明显少于B组(26.6±7.2min)。术后1d，1、2wk，1、3、6mo，A组患眼疼痛、畏光、流泪、异物感、瘙痒等不适感均低于B组，至6mo后两组不适感均消失。A组术后角膜缘干细胞移植片稳定性良好，术后1、3mo并发症发生情况均少于B组。A组未见翼状胬肉复发，B组出现翼状胬肉复发1眼。

结论：原发性翼状胬肉切除术中应用无缝线角膜绷带镜固定角膜缘干细胞移植片简单便捷、安全有效，术后舒适感好，复发率低，与传统缝线法相比可缩短手术时间，有效减轻患者的痛苦。

Application of limbal stem cell transplantation fixed by corneal bandage lens in primary pterygium excision

AIM: To evaluate the application effect of limbal stem cell transplantation fixed by corneal bandage lens with no suture method in primary pterygium excision surgery.

METHODS:Selected 25 patients of 50 eyes with bilateral primary pterygium who were admitted into our hospital from January 2019 to December 2019 for prospective clinical study. Group A(25 eyes)were randomly chosen with one eye of a patient fixed with corneal bandage lens with no suture; and Group B(25 eyes)were chosen with the other eye of a patient using traditional suture method. The incision healing, patient comfort, surgical complications, and postoperative recurrence were observed in both groups after postoperative follow-up for 6mo.

RESULTS: The average operating time for Group A(13.5±2.1min)was significantly less than that of Group B(26.6±7.2min). The results of postoperative follow-up in 1d, 1, 2wk, 1, 3 to 6mo showed that the discomfort such as pain, photophobia, lacrimation, foreign body sensation and itching were lower in Group A than in Group B. The discomfort disappeared in both groups after 6mo. The stability of postoperative corneal rim stem cell transplants was favorable in Group A, and the complications one and three months after surgery were less than those in Group B.

CONCLUSION: The method of banded corneal rim stem cell conjunctival transplantation combined with corneal bandage lens is an effective procedure for the treatment of primary pterygium. It is simple, convenient, safe and effective, the postoperative comfort is good, the recurrence rate is low, compared with the traditional suture method, it can shorten the operation time and effectively reduce the patient''s pains.